摘要
目的探讨宫颈糜烂与宫颈人乳头状瘤病毒(HPV)亚临床感染(SPI)之间的相关性,为临床诊治提供指导性建议。方法选择2013年1月-2014年1月156例宫颈糜烂患者为观察组,选择同期非宫颈糜烂女性74例为对照组,比较两组患者临床指标,采用SPSS 16.0软件进行统计分析。结果观察组SPI发生率26.92%,明显高于对照组;Ⅲ度宫颈糜烂患者SPI发生率高于Ⅰ、Ⅱ度宫颈糜烂患者,比较差异有统计学意义;SPI患者HPV阳性率为71.11%,明显高于非SPI患者,比较差异有统计学意义(P<0.05)。结论宫颈糜烂患者SPI发生率明显较高,同时高危型HPV高发于SPI患者,因此应该以SPI患者为重点监测对象,预防宫颈癌的发生。
OBJECTIVE To investigate the correlation between cervical erosion and HPV subclinical infections so as to provide guidance and advice for clinical diagnosis and treatment.METHODS Totally 156 cases of patients with cervical erosion from Jan.2013 to Jan.2014 were selected as observation group and 74non-cervical erosion patients in the corresponding period were selected as control group.All data were analyzed by SPSS 16.0software.RESULTS The SPI positive rate was 26.92% in the observation group,and it was significantly higher than the control group.Patients with cervical erosion reaching the degreeⅢ had higher SPI positive rate than those with the degree ofⅠ orⅡ.The differences were significant.The HPV positive rate in patients with SPI was 71.11%which was obviously higher than patients without SPI. The differences were significant（P〈0.05）.CONCLUSIONPatients with cervical erosion are easy to suffer from SPI and meanwhile HPV of the high risk type frequently occurrs in SPI-positive patients.Therefore we should focus on the SPI-positive patients to prevent cervical erosion.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2015年第7期1650-1651,1659,共3页
Chinese Journal of Nosocomiology
基金
浙江省医药卫生基金资助项目(2011KYA107)
