摘要
目的探析医院假丝酵母菌属的分布及对氟康唑的敏感性,为防范重点科室患者假丝酵母菌属感染及提高治疗效果提供依据。方法选取医院2012年7月-2013年7月从真菌室分离到的假丝酵母菌属178株作为鉴定对象,采用科玛嘉假丝酵母菌属显色培养基鉴定菌种分布,以及微量稀释法检测对氟康唑的敏感性,采用SPSS 16.0进行统计分析。结果 178株假丝酵母菌属中以白色假绿酵母菌为主,共140株占78.7%;白色假丝酵母菌对氟康唑的敏感率最高,敏感率为97.9%,其次为伏立康唑96.4%,伊曲康唑敏感率最低为82.1%,其他假绿酵母菌属也对氟康唑的敏感率最高。结论医院分离的假丝酵母菌属以白色假丝酵母菌为主,对氟康唑敏感。
OBJECTIVE To discuss and analyze the Candida distribution and drug sensitivity to fluconazole in the hospital so as to provide basis for preventing Candidainfections in key departments in the hospital and improving clinical efficacy.METHODS Totally 178 strains of Candida were separated in fungi room from Jul.2012 to Jul.2013 in the hospital.They were chosen as research objects.CHROMagar Candidachromogenic medium was applied to identify species distribution and microdilution method was applied to test sensibility to fluconazole.All data were analyzed by SPSS 16.0software.RESULTS Among 178 strains of Candida,there were 78.7%（140/178）Candida albicans.Drug sensibility rate of C.albicans to fluconazole was the highest of 97.9%（137/140）,second by voriconazole with the rate of 96.4% and least by itraconazole with the rate of 82.1%.Other Candida was also the most sensitive to fluconazole.CONCLUSION Candidaseparated in our hospital are mainly C.albicans,and they are sensitive to fluconazole.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2015年第7期1544-1546,共3页
Chinese Journal of Nosocomiology
基金
上海市自然科学基金资助项目(13ZR1437900)
