摘要
联合化疗及分子靶向药物治疗成为晚期结直肠癌患者主要的治疗方式。然而,对于经治疗后再次出现疾病进展的患者而言,选择安全有效的二线化疗方案成为必然。目前,国内外大量临床试验对晚期结直肠癌患者二线治疗方案进行了研究,其临床疗效及药物不良反应情况各有差异。因此,了解现有的二线治疗方案疗效并根据患者病情恰当选择对提高晚期结直肠癌患者生存质量,延长其生存期非常重要。
Combined chemotherapy and molecular targeted drug therapy are the main way for the treatment of patients with advanced colorectal cancer. However, choosing the safe and effective second-line chemotherapy regimens is very important for the patients who fail to the initial treatment. At present, second-line treatment was studied in a large number of clinical trials at home and aboard.Nevertheless, the different treatments have the different curative effects and adverse drug reactions.Therefore, getting familiar with the existing treatments and choosing the proper treatments is very important to improve the quality of life and prolong the survival time for the patients with advanced colorectal cancer.
出处
《中华临床医师杂志（电子版）》
CAS
2015年第7期85-89,共5页
Chinese Journal of Clinicians(Electronic Edition)
关键词
结直肠肿瘤
分子靶向治疗
药物疗法
生存质量
Colorectal neoplasms
Molecular targeted therapy
Drug therapy
Quality of life
