摘要
目的探讨游牧部落克里雅人的生理特征及其与代谢综合征低患病率的关系。方法采取随机抽样的方法在克里雅人群中随机选取503人，在新疆和田地区于田县先拜巴扎镇随机选取维吾尔族237人作为对照人群进行流行病学调查，运用24h膳食回顾法进行膳食营养调查。采用病例对照研究的方法，比较2组人群体质和生化指标；比较2组人群代谢综合征的患病率。结果克里雅人组的体重指数小于对照组[（21．25±3．10对22．66±4．18）kg／m2，P〈0．05]。克里雅人组平均收缩压[（110±18对122±21）mmHg，1mmHg=0．133kPa，P〈0．01]、舒张压水平[（73±11对80±15）mmHg，P〈0．01]均低于对照组，总胆固醇[（2．23±1．02对3．26±0．85）mmol／L，P〈0．01]、甘油三酯[（0．98±0．77对1．50±1．29）mmol／L，P〈0．01]、低密度脂蛋白胆固醇[（1．41±0．68）mmol／L，P〈0．01]、空腹血糖[（4．43±1．19对5．56±1．39）mmol／L，P〈0．01]水平低于对照组，有统计学差异。克里雅人组高血压（9．94％对29．11％，P〈0．01）、高血脂、糖尿病（2．2％对11．91％，P〈0．01）患病率均明显低于对照组，有统计学差异。克里雅人代谢综合征检出率为0．6％（3／500），对照人群为13．62％（32／235），克里雅人代谢综合征检出率明显低于对照组（P〈0．01）。克里雅人组摄取的热能明显低于对照组[（1502．341对2106．870）kcal，P〈0．01]。结论克里雅人少肥胖，低体重指数、低血脂、低血压的生理特征，低热量、脂肪、碳水化合物、油脂摄入，少吸烟，饮酒的生活习惯及无污染的自然生活环境是他们代谢综合征患病率低的相关因素，而尤以低热量摄入最为重要。
Objective To investigate the physiological characteristics and the association with low prevalence of metabolic syndrome in Keriyans, a nomadic tribe, in the Taklimakan Desert. Methods An epidemiological survey focusing on diet and standardized physical examinations were made in a randomly selected natural population of 508 Keriyans individuals residing in the Taklimakan desert. In addition, 237 of Uyghur subjects from Yutian county were enrolled as controls. Results Between these two populations, statistical signifieances were observed in body mass index （BMI） [ （ 21.25± 3.10 vs 22.66 ± 4.18 ） kg/m2, P〈0.05 ], blood pressure （ P〈0.01 ）, triglyceride[ TG, （0.98± 0.77 vs 1.50 ± 1.29 ） mmol/L, P〈0.01 ], total cholesterol [ TC, （ 2.23 ±1.02 vs 3.26 ±0.85 ） retool/L, P〈0.01 ], low density lipoprotein-cholesterol [ LDL-C, （ 1.41 ±0.68 ） mmol/L, P〈0.01 ], fasting blood glucose [ （ 4.43±1.19 vs 5.56 ± 1.39 ） retool/L, P〈0.01 ] , fat and salt intake （ P〈0.05 ）. The Keriyans had a low incidence of hypertension（ 9.94% vs 29.11%, P〈0.01 ）, raised blood cholesterol and diabetes mellitus （2.2% vs 11.91% , P〈0.01 ） compared with the control group. The prevalence of metabolic syndrome was 0.6% （ 3/500 ） in Keriyans and 13.62% （32/235） in the control group. The prevalence of metabolic syndrome in Keriyans was much lower than that in the control group （ P〈0. 01 ）. The caloric intake in keriyans group was lower tha than in the control group [ （ 1 502. 341 vs 2106. 870 ） kcal, P 〈 0. 01 ]. Conclusions The preliminary resuks showed that the physiological characteristics with low BMI, blood glucose, and the low levels of TG, TC, LDL-C, as well as they were inured to low salt loading, little smoking and no alcohol drinking, and natural living environment free from pollution, these factors might be associated with the low prevalence of metabolic syndrome in Keriyans. And their low calorie intake might be the most important factor of their low prevale
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2015年第3期210-214,共5页
Chinese Journal of Endocrinology and Metabolism
基金
国家自然科学基金资助项目（30760070）
关键词
游牧部落
克里雅人
生理特征
代谢综合征
Nomadic tribe
Keriyans
Physiological characteristics
Metabolic syndrome
