摘要
目的：探讨儿童临床安全用药的方法，促进合理安全用药。方法采用回顾性调查方法分析我院2012～2013年度上报的98例ADR（药品不良反应）报告，按照患者年龄、性别、给药途径和种类、ADR发生的时间、涉及系统及器官等进行分析。结果6岁以内发生ADR的例数较多，68例（69.39%）；静脉给药方式引发的ADR数量最多，84例（85.71%）；≤30min发生ADR 78例（79.59%）；青霉素、头孢类和β-内酰胺类引起的ADR居多，有65例（66.31%）；ADR的临床表现以皮肤、黏膜及附件的损害最多，有61例（48.41%）。结论儿童ADR的发生率高，抗生素的过度使用引起的ADR，严重威胁儿童的健康，因此应积极建立和加强儿童ADR监测体系。
Objective To study the methods of clinical safe medication in children, to promote the reasonable safe medication. Methods To analyze the adverse drug reaction （ADR） report in 98 children who were retrospectively investigated in our hospital between 2012 and 2013 according to the age, the sex, the route of administration, the occurrence time of ADR, and the interrelated system and organ and so on. Results The ADR report of 68 cases（69.39%）under 6 years old were more major, the ADR report of 84 cases（85.71%）of intravenous administration were the most maximum, the ADR report of 30min and within were 78 cases（79.59%）, the ADR report cause by penicillin, cephalosporin, and β-lactam of 65 cases（66.31%） were in the majority, the ADR report of 61 cases（48.41%） with the clinical manifestation of injury in skin, mucosa, and accessory were the most maximum. Conclusion The incidence of ADR report in children which is caused by overuse of antibiotics is higher. It is better to positively establish and strengthen the monitoring system of ADR in children.
出处
《中国医药科学》
2015年第3期63-65,共3页
China Medicine And Pharmacy
