摘要
目的探讨2型糖尿病患者血清炎症因子的变化及其意义。方法选择80例初诊单纯2型糖尿病患者(T2DM组)和50例健康体检者(对照组),检测两组血清超敏C-反应蛋白(hs-CRP)、肿瘤坏死因子α(TNF-α)、白细胞介素-6(IL-6)、血清淀粉样蛋白A(SAA)、纤溶酶原激活物抑制因子-1(PAI-1)水平。结果 2型糖尿病患者血清hs-CRP、TNF-α、IL-6、SAA、PAI-1水平均高于对照组(P<0.05)。结论在2型糖尿病的发生发展中炎症因子可能具有重要作用。
Objective to investigate the changes and significance of serum infLammatory factors in type 2 diabetes patients. Methods to seLect 80 cases of newLy diagnosed with type 2 diabetes aLone（ t2DM group）and 50 cases of heaLthy check-up （ controL group）. the LeveLs of serum hypersensitive c-reactive protein（ hs-CRP）,tumor necrosis factor aLpha（ tNF-α）,inter-Leukin-6（IL-6）,serum amyLoid a（Saa）,pLasminogen activator inhibitor 1（PaI 1）were detected between the two groups. Results the LeveLs of hs-CRP,tNF-α,IL-6,Saa,PaI-1 in type 2 diabetes were higher than those in the controL group（ P〈0. 05）. Conclusion InfLammatory cytokines may pLay an important roLe in the occurrence and deveLopment of type 2 diabetes.
出处
《临床医学》
CAS
2015年第3期23-24,共2页
Clinical Medicine
关键词
2型糖尿病
炎症因子
临床意义
type 2 diabetes meLLitus
InfLammatory cytokines
CLinicaL significance
