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血管紧张素转换酶抑制剂在动脉粥样硬化患者中的应用评价

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摘要 新近研究表明,血管紧张素转换酶抑制剂除具有高效抗高血压和治疗心力衰竭疗效外,对动脉硬比患者也具有明确的保护作用。其作用机制可能在于对内皮细胞功能的保护,包括促进一氧化氮合成,改善胰岛素抵抗和调节内皮细胞表达组织型纤溶酶激活物和纤溶酶原激活物抑制因子-1等。因此,对血管紧张素转换酶抑制剂应赋予新的适应证。
作者 柯永胜
出处 《国外医学(老年医学分册)》 2002年第4期176-178,共3页 Foreign Medical Sciences(Geriatrics)
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