摘要
目的探讨急性乙型病毒性肝炎抗病毒治疗的方法。方法收集本院急性乙型肝炎患者共7例,分别给予核苷(酸)类似物、或干扰素、或二者联合抗病毒治疗,记录患者治疗前、治疗后4周和12周的肝功能指标、HBV DNA定量、HBV表面标志物水平。结果经积极抗病毒治疗,7例患者均获得病毒学应答,均产生HBs Ab。结论合理、及时的抗病毒治疗可提高急性乙型病毒性肝炎的治愈率,降低慢性化发生率。
Objective To investigate the methods of antiviral treatment about acute hepatitis B. Methods The data of 7 hospitalization patients with acute hepatitis B between June 2011 and March 2013 were collected, restrospectively. The 7 patients were treated with nuclcotide, or IFN-α, or combination of nucleotide and IFN-α. The liver function, HBV DNA, levels of HBsAg and HBsAb at baseline, 4 weeks and 12 weeks after treatment were recorded, respectively. Results After antiviral treatment, all the 7 patients received early virological response and produced HBsAb. Conclusion Antiviral treatment improved the cure rate of acute hepatitis B and reduced the incidence of chronic hepatitis B.
出处
《中华实验和临床感染病杂志（电子版）》
CAS
2015年第1期86-88,共3页
Chinese Journal of Experimental and Clinical Infectious Diseases(Electronic Edition)
