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ESD联合套扎术治疗胃肠道GIST的临床效果 被引量:1

Clinical effects of endoscopic submucosal dissection combined with variceal ligation in treatment of patients with gastrointestinal stromal tumors
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摘要 目的:研究内镜黏膜剥离术联合套扎术治疗胃肠道间质瘤的临床效果.方法:选取2010-08/2014-07新乡医学院第一附属医院消化内科及普外科收治的胃肠道间质瘤患者98例,根据治疗方法分为对照组及观察组,分别给予内镜黏膜剥离术及内镜黏膜剥离术联合套扎术,治疗后观察治疗效果.结果:对照组手术时间、住院时间及治疗费用分别为57.6 min±9.3 min、6.4 d±1.1 d及6324.8元±231.2元;观察组手术时间、住院时间及治疗费用分别为67.9 min±9.1 min,4.9d±1.0 d及5780.9元±214.3元;观察组手术时间长于对照组,但住院时间和治疗费用少于对照组,且差异具有统计学意义(P<0.05).观察组完整切除率高于对照组,穿孔率及术中出血率低于对照组,且差异具有统计学意义(P<0.05).结论:内镜黏膜剥离术联合套扎术治疗胃肠道间质瘤临床效果满意,建议在临床治疗中推广应用. AIM:To analyze the clinical effects of endoscopic submucosal dissection combined with variceal ligation in the treatment of patients with gastrointestinal stromal tumors.METHODS:Ninety-eight patients with gastrointestinal stromal tumors treated at our hospital from August 2010 to July 2014 were selected and divided into either a control group or a treatment group.The control group received endoscopic variceal ligation,and the treatment group received endoscopic submucosal dissection combined with variceal ligation.Clinical effects were observed and compared for the two groups.RESULTS:The operative time was significantly longer in the treatment group than in the control group(57.6 min ± 9.3 min vs 67.9 min ±9.1 min,P〈0.05),while hospital stay time and treatment cost were significantly lower in the treatment group(6.4 d ± 1.1 d vs 4.9 d ± 1.0 d,4324.8 yuan ± 231.2 yuan vs 3780.9 yuan ± 214.3yuan,P〈0.05).The rate of complete excision was significantly higher and the incidences of perforation and bleeding were significantly lower in the treatment group(P〈0.05).CONCLUSION:Endoscopic submucosal dissection combined with variceal ligation is effective in the treatment of patients with gastrointestinal stromal tumors.
出处 《世界华人消化杂志》 CAS 2015年第3期491-494,共4页 World Chinese Journal of Digestology
关键词 胃肠道间质瘤 黏膜剥离术 套扎术 疗效 Gastrointestinal stromal tumors Endoscopic submucosal dissection Endoscopic variceal ligation Clinical effects
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