摘要
目的:研究大负荷力量训练对举重运动员免疫细胞功能的影响。方法:25名优秀男子举重运动员组成训练组、完成5周"二大一调整"式封闭性力量训练(对照组为同龄男大学生);取训练前、每周训练后基础状态静脉血,检测细胞表面CD3、CD4、CD8、CD14、CD16、CD56、HLA-DR、Vα24、Vβ11分子的表达量。结果:1训练第1、3、5周CD3分子的表达量均较训练前下降;第1、4周CD4分子表达量较训练前下降;第1、2周CD8分子表达量较训练前下降;第1周HLA-DR分子表达量较训练前下降。2大负荷力量训练期间CD14、CD16、CD56分子表达量变化无显著性意义。3第1、2、5周Vα24表达量较训练前增加;第3、4周Vβ11表达量较训练前增加。结论:大负荷力量训练导致T细胞相关表面分子表达量下降及NKT细胞相关表面分子表达量增加,提示T细胞功能下降、NKT细胞功能增强。
Purpose: it is to investigate the effects of high-load resistance training on the amount of immune cell surface markers in lifters. Methods : 25 young male lifters were asked to complete a 5-week weight-lifting training program which involved the 2- week training of heavy load with an interval of one week of tapering. And the contrast group included male university students. The venous blood was taken before the training program and after the training of each week. The cell surface markers CD3, CD4, CD8, CD14, CD16, CD56, HLA-DR Va24 and VI324 were tested. Results: ①There was a decreased amount of CD3 in the training week 1, 3 and 5, compared with that before the training; while there was a decreased amount of CD4 in the training week 1 and 4, compared with that before the training ; so was CD8 in the week 1 and 2, and HLA-DR in the week 1. ② There was no significant change in the amount of CD14, CD16, and CD56 during the training. ③There was an increased amount of Vct24 and VI324 in the week 1, 2 and 5, and in the week 3 and 4, respectively. Conclusion: high-load resistance training reduces the amount of T cell related surface markers and enhances the amount of NKT cell related surface markers. This change may indicate that the function of T cells may be decreased and the function of NKT cell may be enhanced under the high-load resistance training.
出处
《上海体育学院学报》
CSSCI
北大核心
2015年第2期46-49,共4页
Journal of Shanghai University of Sport
基金
国家科技攻关计划奥运科技专项基金资助项目(2002BA904B04)