摘要
目的探讨重症肌无力(myasthenia gravis,MG)患者的输血情况。方法回顾性分析2008-01-2013-12北京医院确诊MG患者153例的临床资料,按照临床诊断与输血目的对其输注的血液成分和血量进行分析,并以患者性别和年龄分组后进行对比分析。结果 2008-2013年MG用血人数呈现逐年下降趋势;除2009年外,年度血浆用血总量和人均用血量均大于红细胞,血浆置换单次用浆量最大为14 U,最小仅为6 U。从合并其他疾病MG患者用血分析:贲门癌MG人均用血量最多,红细胞19U、血浆14U,肝占位MG用血小板量最多,为15U,孕产妇MG用血量最少,人均仅用血浆2U,单一MG例数最多,人均红细胞用量仅为1.6U。从分组情况分析,以例数最多的单一MG为例,男、女患者人均用血量分别为4.0U、3.9U,两者差异不大;老年组人均用血量为5.0U,非老年组为3.3U,明显多于非老年组。结论 2008-2013年北京医院MG患者的用血人数及用血量呈逐渐减少趋势。MG患者用血以合并其他疾病MG患者、老年人及单一MG患者血浆置换治疗为主。
Objective Discuss transfusion and blood conservation in patients with myasthenia gravis（MG）.Methods We conducted a retrospective analysis of MG patients diagnosed from January 2008 to December 2013.The clinical data,purpose of blood transfusion,the blood components and volume were analyzed.Subgroup analysis was adopted according to age and sex.Results From 2008 to 2013,the number of MG patients taking blood transfusion showed a declining trend year by year.Except for 2009,total plasma and per capita annual use of plasma were more than the red cells.The largest amount of plasma used in plasma exchanging a time was 14 U,while the minimum was only 6U.Through the analysis of MG combined with other diseases：MG patients with gastric cardiac cancer took the most per capita annual use of blood（19Ured cells,14 U plasma,respectively）.MG patients with focal liver lesions used the most volume of platelet（15 U）.The blood use of MG in pregnant women was the least,with only 2Uplasma per capita.Single MG cases were the most common,in whom the per capita amount of red cells was only 1.6 U.By the analysis of the single MG group,per capita use of blood among male and female patients were 4Uand 3.9Urespectively.There was no significant difference.However,per capita blood use in the elderly group was 5U,while the non elderly group was 3.3U,significantly less than the non elderly group.Conclusions Number of MG patients underwent blood transfusion and volume of blood transfusion gradually decreased in Beijing hospital from 2008 to 2013.MG patients demanding transfusion often combine with other diseases.The elderly is at a higher risk demanding blood transfusion.Single plasma replacement therapy is a main purpose for blood transfusion.
出处
《中国神经免疫学和神经病学杂志》
CAS
2015年第2期89-92,共4页
Chinese Journal of Neuroimmunology and Neurology
关键词
重症肌无力
治疗
输血
myasthenia gravis
therpay
blood transfusion
