摘要
目的探讨中药热奄包外敷联合西药治疗慢性肾衰竭尿毒症期的临床疗效。方法选取慢性肾衰竭尿毒症期患者100例,按随机数字表法将其均分为治疗组和对照组,各50例。治疗组患者给予中药热奄包外敷联合常规西药治疗,对照组患者仅给予常规西药治疗。比较两组患者的疗效,治疗前后收缩压(SBP)和舒张压(DBP),肾功能指标血肌酐(SCr)、血尿素氮(BUN)及内生肌酐清除率(Ccr)水平,以及血尿酸(UA)、血红蛋白(Hb)、血清白蛋白(ALB)及血电解质变化情况。结果治疗组总有效率为62.00%,明显高于对照组的34.00%(P<0.05);治疗后,治疗组患者SBP和DBP较治疗前明显降低,且显著低于对照组(P<0.05);治疗组患者肾功能指标及UA,Hb,ALB,24h尿蛋白、血电解质水平均较治疗前明显改善,且改善程度明显优于对照组(P<0.05)。结论中药热奄包外敷联合西药治疗慢性肾衰竭尿毒症期疗效显著,可有效改善临床症状,值得临床推广。
Objective To investigate the clinical efficacy of traditional Chinese medicine Foment Package external application combined with Western medicine in treating uremic syndrome of chronic renal failure. Methods 100 patients with uremic syndrome in chronic renal failure were selected and divided into the treatment group and the control group,50 cases in each group according to the random number table method. The patients in the treatment group was treated with Chinese medicine Foment Package external application combined with Western medicine,while the patients in control group only used the conventional Western medicine therapy. The curative effects and the changes of blood pressure（ SBP,DBP）,renal function indices of serum creatinine（ SCr）,blood urea nitrogen（ BUN）,creatinine clearance rate（ Ccr）,levels of blood uric acid（ UA）,hemoglobin（ Hb）,serum albumin（ ALB）,24 h urine protein and blood electrolytes before and after treatment were compared between the two groups. Results The total effective rate of the treatment group was62. 00%,which was significantly higher than 34. 00% the control group（ P 0. 05）; SBP and DBP after treatment in the treatment group were significantly decreased compared with those before treatment,and significantly lower than those in the control group（ P 0. 05）; the renal function indices,UA,Hb,ALB,24 h urinary protein and the changes of blood electrolytes after treatment in the treatment group were significantly improved compared with those before treatment,moreover significantly better than those in the control group（ P 0. 05）. Conclusion Traditional Chinese medicine Foment Package external application combined with Western medicine has an obvious curative effect in treating uremic syndrome in chronic renal failure,which can effectively improve the clinical symptoms and is worthy of clinical promction.
出处
《中国药业》
CAS
2015年第6期79-81,共3页
China Pharmaceuticals
基金
河北省中医药科研计划资助项目
项目编号:2014232
关键词
中药热奄包
外敷
西药
慢性肾衰竭
尿毒症期
traditional Chinese medicine foment package
external application
Western medicine
chronic renal failure
uremic syndrome
