摘要
目的:分析小剂量咪达唑仑联合芬太尼在局部麻醉中的具体效果及用药安全性。方法:将笔者所在医院97例需局麻患者按照随机数字表法分为试验组48例和对照组49例,试验组患者应用小剂量咪达唑仑联合芬太尼进行局部麻醉,对照组采用常规药物进行局部麻醉,比较两组患者治疗中血压、心率及镇静效果。结果:两组患者治疗中各时间点血压与心率比较,差异均无统计学意义(P>0.05);但试验组镇静效果Ramsay分级明显优于对照组,治疗中出现不适感较对照组少(P<0.05)。结论:小剂量咪达唑仑联合芬太尼在局部麻醉的应用中具有较好的麻醉镇静效果,且对患者疗效影响小,用药安全性较高。
Objective: To investigate the clinical effect and safety of small dose of Midazolam combined with Fentanyl for local anesthesia. Method: 97 patients with local anesthesia in our hospital were divided into the observation group(48 cases) and the control group(49 cases).The observation group was given small dose of Midazolam combined with Fentanyl for local anesthesia, while the control group was given routine drags for local anesthesia. Blood pressnre(BP), heart rate(HR) and sedative effect of two group were observed.Result: BP and HR for two groups of time points compared to each other, there were no significant differcnces(P〉0.05).Thc sedative effects of the observation group was better than that of the control group, discomfort of the observation group was less than that of the control group(P〈0.05).Conclusion: Small dose of Midazolam combined with Fentanyl for local anesthesia can make good results, better security, and application.
出处
《中外医学研究》
2015年第7期21-22,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH