摘要
目的探讨氯米芬联合吡格列酮对多囊卵巢综合征患者排卵的影响。方法选择80例多囊卵巢综合征患者随机分为观察组和对照组。观察组给予氯米芬联合吡格列酮治疗,对照组给予氯米芬治疗。观察组两组注射重组人绒促性素当天血清雌二醇、黄体生成素、睾酮水平及妊娠情况。结果观察组血清雌二醇水平低于对照组,差异有统计学意义(P<0.05)。观察组成熟卵泡数低于对照组,差异有统计学意义(P<0.05)。观察组妊娠率高于对照组,差异有统计学意义(P<0.05)。结论氯米芬联合吡格列酮能改善多囊卵巢综合征患者的排卵状况,提高妊娠率,治疗效果显著。
Objective To explore the effect of clomiphene combined with pioglitazone on ovulation of polycystic ovary syndrome. Methods 80 patients with polycystic ovary syndrome were selected and randomly divided into observation group and control group.The clomiphene combined with pioglitazone were applied in observation group,the clomiphene was used in control group.The level of serum estradiol,luteinizing hormone,testosterone were detected at the day of injection of recombinant human chorionic gonadotrophin in two groups.The pregnancy rate was observed in two groups.Results The level of serum estradiol in observation group was lower than that in control group,with statistical difference（P〈0.05）.The number of mature follicles in observation group was lower than that in control group,with statistical difference（P〈0.05）.The pregnancy rate in observation group was higher than that in control group,with statistical difference（P〈0.05）. Conclusion Clomiphene combined with pioglitazone can improve ovulation in patients with polycystic ovary syndrome,improve the pregnancy rate,the treatment effect is significant.
出处
《中国当代医药》
2015年第6期117-118,共2页
China Modern Medicine
关键词
多囊卵巢综合征
氯米芬
吡格列酮
Polycystic ovary syndrome
Clomiphene
Pioglitazone
