摘要
目的:探讨中医护理对功能性消化不良(Functional dyspepsia,FD)肝郁脾虚证患者脑肠肽CCK、5-HT含量的影响。方法:选择确诊为FD肝郁脾虚证的60例患者并随机分为两组,对照组(多潘立酮组)与治疗组(多潘立酮片+中医情志护理)各30例,均治疗23 d。采用放射免疫法测定两组患者治疗前后空腹血CCK、5-HT水平。结果:治疗组、对照组总有效率分别为93.33%、76.67%,两组比较差异无统计学意义;但治疗组显效率为70.00%,明显高于对照组的36.67%(P<0.05)。与治疗前比较,治疗组与对照组中医证候积分差异均有统计学意义(P<0.01);治疗后两组比较,差异有统计学意义(P<0.05)。两组治疗后血CCK、5-HT较治疗前均降低,且差异有统计学意义(P<0.05)。结论:中医情志护理治疗功能性消化不良肝郁脾虚证可能通过降低血中CCK、5-HT的含量,从而改善临床症状。
Objective： To study the influence of TCM nursing on CCK of braingut peptides and 5-HT of liver-stagnation and spleen-deficiency syndrome with functional dyspepsia. Methods： 60 Patients were selected according to the standard of functional dyspepsia of liver-stagnation and spleen-deficiency syndrome, were randomly assigned to control group （domperidone group, n=30） and treatment group （domperidone＋TCM emotional nursing, n-30） for 23 days. The changes of clinical symptoms and signs were observed before and after therapy, and the changes of serum CCK,5-HT were detected. Results： Total effective rate in the treatment group and the control group was 93.33% and 76.67% respectively, there was no significant difference between the two groups; but the obvious effective rate was 70.00% in the treatment group, it was significantly higher than that of the control group （36.67%, P〈0.05）. The difference of TCM syndrome was statistically significant （P〈0.01） pre and post treatment in two groups, and there was statistically significant （P〈0.05） between two groups after treatment. After treatment CCK and 5-HT were decreased in two groups, the difference after treatment between two groups was statistically significant （P〈0.05）. Conclusion： TCM Emotional nursing in treating functional dyspepsia of liver-stagnation and spleen-deficiency syndrome may improve the clinical symptoms through reducing serum CCK and 5-HT,
出处
《实用中西医结合临床》
2015年第1期82-84,共3页
Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
基金
湖南省科学技术厅科技计划项目(编号:2013FJ4053)
湖南省中医药管理局中医护理特色技术重点研究室建设项目(编号:2014003)
关键词
功能性消化不良
肝郁脾虚证
中医护理
CCK
5-HT
Functional dyspepsia
Liver-stagnation and spleen-deficiency syndrome
Traditional chinese medicine nursing
CCK
5 -HT
