摘要
目的观察射频消融术治疗心动过速性心肌病的临床效果。方法将92例心动过速性心肌病患者依据患者意愿分为研究组52例和对照组40例,研究组使用射频消融术治疗,对照组使用地高辛0.25mg,静脉滴注,每日1次;卡托普利25mg,口服,3次/d;胺碘酮5mg/kg快速静脉滴注,45min后改为维持量10mg/(kg·d)静滴至心功能改善。对比两组患者的临床疗效和治疗前后的左室射血分数(LVEF)、左室舒张末内径(LVEDD)和血浆NT-proBNP水平。结果研究组心功能恢复情况显著优于对照组(P<0.05)。治疗前两组患者的LVEF、LVEDD和NT-proBNP水平无统计学差异(均P>0.05);治疗后研究组和对照组的LVEF、LVEDD和NT-proBNP水平分别为59.5±8.9、47.5±10.1、(51.8±6.9)mm和(54.2±5.7)、(478.4±753.2)、(793.9±964.5)pg/ml,均具有统计学差异(均P<0.05)。结论使用射频消融术治疗心动过速性心肌病的临床效果较药物治疗更优,具有临床应用价值。
Objective To study the clinical effects of radiofrequency ablation on tachycardia-induced cardiomyopathy.Methods 92 patients with tachycardia-induced cardiomyopathy were randomly divided into study group and control group.52 patients in study group were treated with radiofrequency ablation.40 patients in control group were treated with digoxin 0.25 mg iv qd,captopril 25 mg po tid,amiodarone 5mg/kg,intravenous dirp quickly after 45 min maintain10mg/（kg·d）until the relief of cardiac function disorder.The left ventricular ejection fraction（LVEF）,left ventricular end-diastolic dimension（LVEDD）and NT-proBNP level were studied in those two groups.Results The recovery of cardiac function in study group was better than that in control group（P〈0.05）.The LVEF,LVEDD and NT-proBNP level was 59.5±8.9and 47.5±10.1,（51.8±6.9）mm and（54.2±5.7）mm,（478.4±753.2）pg/ml and（793.9±964.5）pg/ml respectively.All indexes were statistic different（P〈0.05）.Conclusion The treatment of radiofrequency ablation on tachycardia-induced cardiomyopathy has a better clinical effects than drug therapy.
出处
《西部医学》
2015年第3期374-376,共3页
Medical Journal of West China
基金
新疆维吾尔自治区科技攻关和重点科技项目(200630129)
关键词
心动过速性心肌病
射频消融术
药物治疗
Tachycardia-induced cardiomyopathy
Radiofrequency ablation
Drug treatment
