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上皮性卵巢癌复发的影响因素分析 被引量:12

Analysis of influence factors of epithelial ovarian cancer recurrence
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摘要 目的探讨上皮性卵巢癌患者复发的影响因素。方法收集上皮性卵巢癌患者的临床与病理资料,并随访以了解其是否复发。采用COX回归分析探讨复发的影响因素。结果共纳入研究对象173例,随访时间平均(59.4±10.86)个月,共有91例复发(52.6%),76例死亡(43.9%),生存时间平均(32.1±6.75)个月。COX多元回归分析结果显示,残瘤大小、肿瘤分期、病理类型、组织分化、是否清扫淋巴结为影响上皮性卵巢癌复发的影响因素。结论上皮性卵巢癌复发的影响因素包括残瘤大小、肿瘤分期、病理类型、组织分化及是否清扫淋巴结。 Objective To explore the influence factors of epithelial ovarian cancer recurrence.Methods The clinical and patholog-ical data of patients with epithelial ovarian cancer in our hospital were collected,and their cancer recurrence during the follow-up period were recorded,then the influence factors of recurrence were explored by Cox regression analysis.Results A total of 173 cases were included in the study,and during the follow-up period (59.4 ±10.86 months on average),91 (52.6%)cases recurred and 76 (43.9%)cases died, with mean survival time (32.1 ±6.75 )months.Multivariate Cox regression analysis revealed that,the residual tumor size,tumor stage, pathological type,histological differentiation,lymph node dissection or non-dissection were the influence factors of epithelial ovarian cancer recurrence.Conclusion Residual size,tumor stage,pathological type,histological differentiation,whether lymph node dissection are influ-ence factors of epithelial ovarian cancer recurrence.
作者 叶俊良 高杨
出处 《安徽医学》 2015年第2期167-170,共4页 Anhui Medical Journal
关键词 上皮性卵巢癌 复发 预后 影响因素 Epithelial ovarian cancer Recurrence Prognosis Influence factor
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  • 1郄明蓉,侯敏敏,曹泽毅,张崇淑,彭芝兰,王红静,郑艾.卵巢恶性肿瘤年轻患者保留生育功能手术的效果评价[J].中华妇产科杂志,2006,41(4):233-236. 被引量:15
  • 2Tang H J, Jin X, Wang S, et al. A small molecule compound inhibits AKT pathway in ovarian cancer cell lines[J]. Gynecol Oncol,2006,100(2) :308-317. 被引量:1
  • 3Brandwijk RJ,Dings RP, van der Linden E, et al. Anti-angio genesis and anti-tumor activity of recombinant anginex[J]. Bio chem Biophys Res Corrtmun, 2006,349 (3) : 1073-1078. 被引量:1
  • 4Suga S, Kato K, Ohgami T, et al. An inhibitory effect on cell proliferation by blockage of the MAPK/estrogen receptor/ MDM2 signal pathway in gynecologic cancer[J]. Gynecol Oncol, 2007,105 (2) : 341-350. 被引量:1
  • 5Dinh P, Harnett P, Piccart-Gebhart MJ, et al. New therapies for ovarian cancer: cytotoxics and molecularly targeted agents [J].Crit Rev Oncol Hematol,2008,67(2) : 103-112. 被引量:1
  • 6Geisler JP, Linnemeier GC, Thomas A J, et al. Extreme drug resistance is eommon after prior exposure to paelitaxel[J]. Gyne col Oncol, 2007,106(3) : 538-540. 被引量:1
  • 7Tinker AV, Gebski V, Fitzharris B, et al. Phase II trial of weekly docetaxel for patients with relapsed ovarian cancer who have previously received paclitaxel-ANZGOG[J]. Gyneeol Oncol,2007,104(3) :647-653. 被引量:1
  • 8Linch M,Stavridi F, Hook J, et al. Experience in a UK cancer centre of weekly paelitaxel in the treatment of relapsed ovarian and primary peritoneal cancer [J]. Gyneeol Oncol, 2008, 109 ( 1 ) : 27-32. 被引量:1
  • 9Ho EA,Soo PL, Allen C, et al. Impact of intraperitoneal sustained delivery of paclitaxel on the expression of P glycoprotein in ovarian tumors[J]. J Control Release, 2007,117 ( 1 ) : 20-27. 被引量:1
  • 10Katsaros D,Oletti MV, Rigauh de la Longrais IA, et al. Clinical and pharmacokinetic phase II study of pegylated liposomal doxorubicin and vinorelbine in heavily pretreated recurrent ovarian carcinoma[J]. Ann Oncol, 2005,16 (2) : 300-306. 被引量:1

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  • 1潘一红,陶俊贞,吕荣伟,金芙蓉,林慧敏,周丹红,陶德友.吉西他滨联合卡铂在复发性上皮性卵巢癌治疗中的应用[J].上海交通大学学报(医学版),2011,31(4):481-483. 被引量:6
  • 2代聪伟,阴梅云.紫杉醇多药联合治疗晚期卵巢癌[J].国际肿瘤学杂志,2006,33(6):456-459. 被引量:4
  • 3苗卉.上皮性卵巢癌Survivin蛋白的表达及拓扑替康对其表达的影响[J].国际肿瘤学杂志,2006,33(12):945-947. 被引量:4
  • 4Rosai J. Peritoneum, retroperitoneum, and related struc- tures [M]// Rosai and Ackerman's Surgical Pathology. 10th ed. Edinburgh, Mosby,2011:2400-2401. 被引量:1
  • 5Douglas GW, Kastin AJ, Huntington RW Jr. Carcinoma arising in a retroperitoneal Mtillerian cyst, with widespread metastasis during pregnancy[J]. Am J Obstet Gynecol,1965,91:210-216. 被引量:1
  • 6Feng J, Liu H, Chen D. Primary retroperitoneal mutinous cystadenocarcinoma in a male patient: a rare case report [J]. Hippokratia,2013,17(3):271-273. 被引量:1
  • 7Matsubara M, Shiozawa T, Tachibana R, et al. Primary retroperitoneal mucinous cystadenoma of borderline ma- lignancy: a case report and review of the literature[J]. IntJ Gynecol Pathol,2005,24(3):218-223. 被引量:1
  • 8Uematsu T, Kitamura H, Iwase M, et al. Ruptured retroperitoneal mucinous cystadenocarcinoma with syn- chronous gastric carcinoma and a long postoperative sur- vival: case report[J]. J Surg Oncol,2000,73(1):26-30. 被引量:1
  • 9Hanhan HM, Gungorduk K, Ozdemir A, et al. Primary retroperitoneal mucinous cystadenocarcinoma during pregnancy[J]. J Obstet Gynaecol,2014,34(6):535-538. 被引量:1
  • 10Tapper EB, Shrewsberry AB, Oprea G, et al. A unique benign mucinous cystadenoma of the retroperitoneum: a case report and review of the literature[J]. Arch Gynecol Obstet,2010,281(1): 167-169. 被引量:1

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