摘要
目的应用频域OCT测量正常学龄期儿童的黄斑区视网膜厚度。方法选取6~12岁儿童108人,以最佳矫正远视力≥1.0、最佳矫正近视力Jr1、球镜屈光度范围(-1.00^+1.00 D)、柱镜屈光度范围(-1.00^+1.00 D)为纳入标准,最终选取213眼。应用Cirrus HD-OCT的200×200扫描模式和512×218扫描模式对受试者双眼黄斑区视网膜进行检查,测量黄斑中心视网膜厚度(central subfield thickness,CST)、黄斑区视网膜容积(macular volume,MV)、黄斑区平均视网膜厚度(average macular thickness,AMT)及九分区模式视网膜厚度。结果两种扫描模式下黄斑区视网膜厚度值差异均无统计学意义(均为P>0.05)。左右眼差异无统计学意义(均为P>0.05)。男童CST(240.68±16.57)μm厚于女童(234.51±18.65)μm(P=0.040),且男童内环各分区视网膜厚度均厚于女童(均为P<0.05)。结论本研究应用HD-OCT测量正常儿童AMT,为确定国人学龄期儿童AMT正常值及疾病诊断提供参考,提示临床注意性别差异。
Objective To assess the macular retinal thickness values in normal school-age children with spectral domain optical coherence tomography （SD-OCT）. Results Cross-sectional study. 108 normal children （213 eyes）aged from 6 years to 12 years with best-corrected distant visual acuity ≥ 1.0 ,best-corrected near visual acui- ty Jrl, spherical equivalent from - 1.00 D to ＋ 1.00 D and astigmatism equivalent from - 1.00 D to ＋ 1.00 D were included. Scan patterns of 200 ×200 cube and 512 ×218 cube of Cirrus HD-OCT were performed in each eye. Central subfield thickness, macular vol- ume, average macular thickness and average retinal thickness of every segment of nine areas were measured. Results There was no statistical difference in average macuiar thickness between two scan patterns （ all P 〉 0.05 ）, and the values between right and left eye was not significant different （ all P 〉 0.05 ）. Central subfield thickness of male was （240.68 ± 16.57） μm, which was thicker than female （234.51 ± 18.65） μm （P = 0.040）. Each segment of retinal thickness of inner circle in male was thicker than those in female （ all P 〈 0.05）. Conclusions The average macular thickness assessed by SD-OCT in the normal school-age children in this study provide the reference for deter- mining the normal value and diagnosing some diseases, and the difference between male and female children should be concerned.
出处
《眼科新进展》
CAS
北大核心
2015年第2期180-182,共3页
Recent Advances in Ophthalmology
关键词
黄斑
视网膜厚度
频域OCT
儿童
macular
retinal thickness
spectral domain optical coherence tomo-graphy
children
