摘要
目的了解屈光参差性弱视患儿黄斑中心凹平均厚度与视网膜神经纤维层平均厚度及其与视力的关系。方法对本院门诊确诊为远视性屈光参差性弱视的17例患儿,应用相干光断层扫描仪(OCT)检测双眼黄斑中心凹平均厚度与视网膜神经纤维层平均厚度。弱视眼为病例组,优势眼为对照组,用SPSS13.0统计软件分析两组黄斑中心凹平均厚度和视网膜神经纤维层平均厚度的差异。结果弱视眼黄斑中心凹平均厚度平均(153.82±15.10)μm,优势眼黄斑中心凹平均厚度平均(140.65±19.50)μm。弱视眼视网膜神经纤维层平均厚度(114.40±19.94)μm,优势眼视网膜神经纤维层平均厚度(111.16±11.98)μm。优势眼组与弱视眼组黄斑中心凹平均厚度的差异有统计学意义(t=3.02,P=0.008),平均差异(13.18±18.01)μm。优势眼组与弱视眼组视网膜神经纤维层平均厚度差异无统计学意义(t=0.64,P=0.54)。结论屈光参差性患儿弱视眼视力与黄斑中心凹平均厚度有一定关系,随视力提高厚度有否改变及其厚度与中心凹的X通道的关系等有待进一步探索。OCT技术为非侵入性,可靠、安全,可作为儿童弱视的一种辅助检测方法,能否用于客观评估弱视预后及检测弱视治疗效果有待进一步研究。
Objective To research the relation among vision and retinal thickness of fovea centralis and of peripapillary nerve fiber layer（ RNFL）. Methods Seventeen patients with hyperopic anisometropie amblyopia were included. The retinal thickness of fovea centralis and of RNFL was measured by optical coherence tomography （ OCT ） and compared between the amblyopia eye and the normal eye. Results The mean retinal thickness of fovea eentralis was 153.82 ± 15.10 μm and 140.65 ± 19.50 μm, and the mean RNFL thickness was 114.40 ± 19.94 μm and 111.16 ± 11.98 μm,in the amblyopia eye and the normal eye. OCT assessment revealed a significantly thicker retinal thickness of fovea centralis in hyperopic amblyopia eye（ t =3.02, P =0.008） ,but no statistically significant difference was found in RNFL（ t =0.64, P = 0.54）. Condusion The vision of the amblyopia eye may involve the retinal thickness of fovea centralis. However,further evaluation is needed.
出处
《临床眼科杂志》
2009年第2期122-124,共3页
Journal of Clinical Ophthalmology
关键词
弱视
屈光参差性
相干光断层扫描
Amblyopia
Anisometropic
Optical coherence tomography
