期刊文献+

曲美他嗪治疗冠心病舒张性心力衰竭的疗效 被引量:6

原文传递
导出
摘要 目的观察曲关他嗪治疗冠心病舒张性心力衰竭(DHF)的临床疗效。方法将74例DHF冠心病患者随机分为两组,每组36例。对照组给予常规药物治疗,观察组在对照组基础上加用曲美他嗪20mg,口服,3次/d,疗程为3个月。观察两组疗效。结果治疗后观察组心力衰竭症状缓解时间为(7.3±4.2)d,短于对照组的(10.6±4.7)d,观察组ST—T改善程度高于对照组,差异均有统计学意义(P〈0.05)。治疗后观察组各指标均优于对照纽(P〈0.05)。结论曲美他嗪治疗冠心病DHF患者可显著改善心脏的舒张功能,提高生活质量,临床疗效肯定。
作者 陈文丽
出处 《中国实用医刊》 2015年第5期97-98,共2页 Chinese Journal of Practical Medicine
  • 相关文献

参考文献3

二级参考文献34

  • 1庄海舟,沈潞华,刘冲.曲美他嗪对心力衰竭大鼠心功能自由基代谢心肌纤维化及心肌超微结构的影响[J].临床心血管病杂志,2006,22(9):541-544. 被引量:14
  • 2Liu X,Gai Y,Liu F,et al.Trimetazidine inhibits pressure overload-induced cardiac fibrosis through NADPH oxidase-ROS-CTGF pathway[J].Cardiovasc Res,2010,88:150-158. 被引量:1
  • 3Fragasso G,Piatti M PM,Monti L,et al.Short and long-term beneficial effects of trimetazidine in patients with diabetes and ischemic cardiomyopathy[J].Am Heart J,2003,146:18-25. 被引量:1
  • 4Napoli PD,Taccardi AA,Barsotti A,et al.Long term cardioprotective action of trimetazidine and potential effect on the inflammatory process in patients with ischaemic dilated cardiomyopathy[J].Heart,2005,91:161-165. 被引量:1
  • 5Kady El,SabbanK El,Gabaly M,et al.Effects of trimetazidine on myocardial perfusion and the contractile response of chronically dysfunctional myocardium in ischemic cardiomyopathy:a 24-month study[J].Am J Cardiovasc Drugs.2005,5:271-278. 被引量:1
  • 6Tuunaen H,Engblom E,Naum A,et al.Trimetazidine,a metabolic modulator,has cardiac and extracardiac benefits in idiopathic dilated cardiomyopathy[J].Circulation,2008,118:1250-1258. 被引量:1
  • 7Fragasso G,Palloshi A,Puccetti P,et al.A randomized clinical trial of trimetazidine,a partial free fatty acid oxidation inhibitor,in patients with heart failure[J].J Am Coll Cardiol,2006,48:992-998. 被引量:1
  • 8Fragassol G,Perseghin G,De Cobelli F,et al.Effects of metabolic modulation by trimetazidine on left ventricular function and phosphocreatine/adenosinetriphosphate ratio in patients with heart failure[J].Eur Heart J,2006,27,942-948. 被引量:1
  • 9Neubauer S,The failing heart-an engine out of fuel[J].N Engl J Med,2007,356:1140-1151. 被引量:1
  • 10Napoli DP,Taccardi A.Trimetazidine:the future of cardiac function[J].Future cardiology,2009,5:421-424. 被引量:1

共引文献107

同被引文献32

引证文献6

二级引证文献155

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部