脂蛋白相关磷脂酶A2特性及与疾病发生关系的概况被引量：3

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摘要脂蛋白相关磷脂酶 A2（lipoprotein-associated phospholipase A2，Lp-PLA2）也叫血浆血小板活化因子乙酰水解酶（pPAF-AH），是冠心病和肿瘤发生的一个重要炎症标志物，与粥样斑块的形成密切相关，其生物学变异小，特异性高，很少受其它炎症标志物影响，可作为临床诊治疾病新的检测指标。由于 Lp-PLA2主要具有促进动脉粥样硬化作用，降低体内Lp-PLA2浓度和活性将可能成为治疗冠心病和预防心血管疾病的一个新的研究方向。另外其对肿瘤的早期监测与个体化治疗也将有帮助。

作者王敬军刘胜林田刚

机构地区天津市蓟县人民医院检验科天津市西青医院检验科天津公安医院检验科

出处《现代检验医学杂志》 CAS 2014年第6期71-73,共3页 Journal of Modern Laboratory Medicine

关键词脂蛋白相关磷脂酶A2 冠心病肿瘤

分类号 R446.1 [医药卫生—诊断学]

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