摘要
目的探讨急性颅脑损伤病人血糖水平与病人病情及预后的关系。方法检测120例排除糖尿病病史急性颅脑损伤病人入院随机血糖,以及入院2周内空腹血糖平均值(第1周每天检测病人晨6:00空腹血糖,第2周隔天检测病人晨6:00空腹血糖,血糖持续高于10mmol/L者应用胰岛素控制血糖,住院不足2周出院或死亡者取在院期间晨6:00空腹血糖平均值),分析病人入院随机血糖水平与病人入院格拉斯哥昏迷评分(GCS)、入院2周空腹血糖平均值与病人1个月后格拉斯哥预后评分(GOS)的关系。结果病人入院随机血糖3.9~6.0mmol/L者GCS评分较高,血糖6.1~10.0mmol/L者GCS评分低于血糖3.9~6.0mmol/L者,血糖>10.0mmol/L者的GCS评分低于其他两组,差异有显著性(F=14.579,P<0.05)。入院随机血糖与病人入院时病情(GCS)呈负相关(r=-0.567,P<0.05)。入院2周平均空腹血糖3.9~6.0mmol/L者、6.1~10.0mmol/L者、>10.0mmol/L者GOS评分依次降低,差异有显著性(F=57.560,P<0.05)。入院2周平均空腹血糖与病人1个月预后(GOS)呈负相关(r=-0.737,P<0.05)。结论急性颅脑损伤后病人血糖可作为判定病情及预后的指标,入院随机血糖越高,病情越重;入院2周平均空腹血糖越高,预后越差。
Objective To explore the relationship between the level of blood glucose and patient＇s condition and progno- sis in acute craniocerebral trauma （ACCT）. Methods Blood sugar was detected in 120 patients with ACCT on admission, and the average value of fasting blood glucose （FBG） in two weeks after admission was calculated. In the first week, the FBG was de- tected at 6 a.m. every day, and in the second week it was detected every other day at the same time. For those FBG consistently higher than 10 retool/L, insulin was applied to control the blood sugar. The relationship between blood sugar and Glasgow Coma Scale （GCS） on admission and the relationship between average blood sugar in two weeks and GCS after one month of admission were analyzed. Results For patients whose random blood sugar was 3.9--6.0 mmol/L, the score of GCS was higher than those with blood sugar of 6.1-10.0 retool/L, those with blood sugar higher than 10 mmol/L, the score of GCS the lowest, the diffe- rence was significant （F ： 14.579, P 〈0.05）. The random blood glucose levels on admission were negatively correlated with GOS of the patients （r =- 0. 567, P 〈 0.05）. The GOS in patients with an average blood glucose levels of 3.9- 6.0 retool/L, 6.1- 10.0 mmol/L and that higher than 10 mmol/L in two weeks after two weeks of admission was in a decreasing manner, the diffe- rences being statistically significant （F ~ 57.560, P ~0.05）. There was a negative correlation between the two-week average level of fasting blood glucose and GOS （r： --0.737,P^0.05）. Conclusion The level of blood glucose in patients with acute eraniocere- bral trauma can be used as an index to predict their condition and prognosis. The higher level of blood glucose on admission means the patients＇ condition being serious and the higher average level of fasting blood glucose means the poorer prognosis.
出处
《青岛大学医学院学报》
CAS
2015年第1期83-84,87,共3页
Acta Academiae Medicinae Qingdao Universitatis
关键词
颅脑损伤
血糖
预后
craniocerebral trauma blood glucose prognosis
