摘要
高血压发病的具体机制尚不明确,氧化应激作为高血压发病机制之一,为其预防和治疗提供了靶点,通过调节机体氧化应激水平治疗高血压可能成为新的方向。然而使用作用途径单一的抗氧化剂,很难全面应对复杂的氧化应激过程。因此,全面了解氧化应激和高血压发病机制之间的关系,明确氧化系统及抗氧化系统的各种指标在高血压发生和发展过程中的具体作用,联合运用多靶点、多途径的抗氧化剂或提升机体抵御氧化应激能力的药物,或许能更好地控制高血压。
The specific mechanism of Hypertension disease is not yet clear. Oxidative stress as one of the pathogenesis of hypertension,prove the target for prevention and treatment of Hypertension. Adjusting the oxidative stress in treating high blood pressure may become a new direction. But single use of antioxidant can hardly to repy complex process of oxidative stress. Therefore,a comprehensive understanding of the relationship between oxidative stress and the pathogenesis of hypertension,the specific function of oxidation system and antioxidant system index in the process of occurrence and development of high blood pressure,joint use of multiple targets,multiple ways of antioxidants or enhance the capacity of the body against oxidative stress,may be better able to control high blood pressure.
出处
《中医学报》
CAS
2015年第1期101-104,共4页
Acta Chinese Medicine
基金
国家重点研究计划(973)项目(2012CB518505)
国家自然科学基金项目(81202738)
天津市卫生局中医中西医结合科研项目(11036)
关键词
氧化应激
高血压
氧化系统
抗氧化系统
oxidative stress
hypertension
oxidation system
anti-oxidant system
