摘要
目的观察铁皮石斛与玉竹及其配方的抗疲劳作用。方法将ICR小鼠25只随机分为阴性对照组、单味铁皮石斛组、单味玉竹组、铁皮石斛复方组、玉竹复方组,每组5只,连续给药1周(7天)后进行游泳实验,小鼠休息2天后,灌胃相应药物30min后进行耐缺氧实验,记录数据,对比并分析各组的差异。结果小鼠体质量增长、游泳时间和耐缺氧时间,呈现复方铁皮石斛组[(8.60±0.69)g、(9.86±0.35)min、(28.66±1.28)min]>复方玉竹组[(7.46±0.55)g、(9.02±0.45)min、(26.78±1.27)min]>单味铁皮石斛组[(6.40±1.14)g、(8.78±1.00)min、(24.52±2.32)min]>单味玉竹组[(5.60±1.20)g、(8.56±0.69)min、(23.38±2.21)min]>对照组[(4.84±0.98)g、(7.44±0.91)min、(19.92±2.12)min],且复方组明显高于其它三组(P<0.05)。结论铁皮石斛和玉竹均有显著的抗疲劳作用,单味玉竹的抗疲劳作用略亚于单味铁皮石斛,铁皮石斛复方的抗疲劳效果明显优于玉竹复方。
Objective To compare the anti-fatigue effects of Dendrobium candidum with that of Polygonatum.Methods Twenty-five ICR mice were randomly divided into negative control group, single herb Dendrobium candidum group, single herb Polygonatum group, Dendrobium candidum compound group, and Polygonatum compound group, with 5 mice in each group. All group were given the corresponding drugs for consecutive 7 days, then underwent the swimming test. After that, all mice rested for 2 days, then were intragastrically given the corresponding drug for 30 min and underwent hypoxia experiment. The differences between 2 groups were analyzed. Results The increase in weight was the biggest and swimming time and hypoxia-tolerant time were the longest in Dendrobium candidum compound group（8.60±0.69 g, 9.86±0.35 min, 28.66±1.28min）, followed by those in Polygonatum compound group（7.46±0.55 g, 9.02±0.45 min, 26.78±1.7min）, then those in single herb Dendrobium candidum group（6.40±1.14 g,8.87±1.00 min, 24.52±2.32min）, single herb Polygonatum group（5.60±1.20 g, 8.56±0.69 min, 2.38±2.21min）, with the least in Negative control group（4.84±0.98 g, 7.44±0.91 min, 19.92±2.12min）. There were significant differences between Dendrobium candidum compound group and single herb group and negative control group and between Dendrobium candidum compound group and Polygonatum compound group（P〈0.05）. Conclusion Both of Polygonatum and Dendrobium candidum have obvious anti-fatigue effect. The effect of single herb Polygonatum is slightly minor than that of single herb Dendrobium candidum. The Anti-fatigue effect of Dendrobium candidum compound evidently surpasses that of Polygonatum Compound.
出处
《浙江中西医结合杂志》
2015年第2期127-129,共3页
Zhejiang Journal of Integrated Traditional Chinese and Western Medicine
关键词
铁皮石斛
玉竹
白术
抗疲劳
Dendrobium candidum
Polygonatum
Atractylodesv
Anti-fatigue effects
