摘要
目的探讨女性Colles骨折患者性激素与应激激素水平并进行相关性分析.方法选择女性Colles骨折患者85例,根据VAS评分分为轻度组、中度组、重度组,分别有30、29、26例.分别检测3组性激素、应激激素水平.结果中度组患者VAS评分P较对照组差异有统计学意义(P<0.05),重度组VAS评分、TT、P较轻度组及中度组差异有统计学意义(P<0.05).中度组患者肾上腺素、去甲肾上腺素较轻度组均有显著性升高(P<0.05),重度组肾上腺素、去甲肾上腺素较轻度组及中度组均有显著性差异(P<0.05).肾上腺素与TT、P显著负相关(P<0.05),与E2未见显著相关性(P>0.05).去甲肾上腺素与P显著负相关(P<0.05),与TT、E2未见显著相关性(P>0.05).结论女性Colles骨折患者性激素水平失调与疼痛导致的应激状态密切相关,不同激素水平参与疼痛的调节.
Objective To investigate the sex hormone and stress hormone levels in female patients with Colles fracture and their correlations. Methods 85 cases of female patients with Colles fracture were divided into mild （30 cases） , moderate （29 cases） and severe （26 cases） groups according to VAS scores. Sex hormone and stress hormone levels were detected. Results There were significant differences in VAS score and progestin （P） level between moderate group and control group （P〈0.05） . Compared with mild and moderate groups, VAS score, total testosterone （TT） and P levels in severe group showed significant differences （P〈0.05） . Epinephrine and norepinephrine in moderate group were significantly higher than those in mild （P〈O.05）, and those in severe group showed significant differences compared with mild and moderate groups （P〈0.05） . Epinephrine was negatively correlated with TF and P （P〈0.05）, while was not correlated with estradiol （E2） （P 〉 0.05） . Norepinephrine was negatively correlated with P （P〈0.05）, while was not correlated with TT and E2 （P 〉 0.05） . Conclusion Stress hormone levels in Colles fracture patients are closely related to the stress state, and the hormone levels participate in the regulation of pain.
出处
《昆明医科大学学报》
CAS
2015年第1期133-135,共3页
Journal of Kunming Medical University
基金
云南省应用基础研究计划基金资助项目(2011FB150)
