摘要
目的:探讨欣母沛(卡前列素氨丁三醇)用于瘢痕子宫阴道分娩预防产后出血的有效性、安全性。方法:2010年7月-2013年7月,本院瘢痕子宫阴道分娩的产妇共90例。随机数字表法分为试验组42例和对照组48例。试验组在胎儿娩出后常规肌注缩宫素的基础上,同时应用欣母沛肌肉注射,对照组则同时应用益母草针肌肉注射。比较两组产后2 h及24 h出血量、产后出血发生率、药物不良反应发生率。结果:试验组与对照组的产后2 h出血量、24 h出血量、产后出血发生率比较,试验组均低于对照组,两组比较差异有统计学意义(P<0.05)。试验组与对照组的不良反应发生率比较,差异无统计学意义。结论:欣母沛对于瘢痕子宫阴道分娩产妇发生产后出血的防治,较益母草针疗效明显,副反应少。
Objective： To discuss the effectiveness, safety on hemabate（romethamine） for prevention of postpartum hemorrhage of scar uterine vaginal delivery. Method： 90 scar uterus vaginal delivery patients were chosen in our hospital from 2010 July to 2013 July, and randomly divided into experimental group（42 cases） and control group（48 cases）. In the experimental group, after delivery of fetusconventional they were given intramuscular injection of oxytocin and hemabate intramuscular injection, the control group at the same time was given motherwort needle intramuscular injection. Two hours and 24 hours postpartum hemorrhage, the incidence of postpartum hemorrhage, the incidence of adverse drug reactions of two groups were compared. Result： The experimental group and control group of 2 hours postpartum hemorrhage 24 hours postpartum hemorrhage, the incidence of postpartum hemorrhage the experimental group were all less than those of the control group, there were significant differences between the two groups（P〈0.05）. The incidence of adverse reaction in the experimental group and the control group was 4.8% and 2.1%, there was no significant difference between the two groups. Conclusion： Hemabate for prevention of postpartum hemorrhage of scar uterine vaginal delivery is more obvious curative effect and less side reaction than motherwort needle.
出处
《中国医学创新》
CAS
2015年第1期139-141,共3页
Medical Innovation of China
关键词
欣母沛
瘢痕子宫
宫缩乏力
产后出血
Hemabate
Scar uterine
Uterine atony
Postpartum hemorrhage
