摘要
目的探讨乳酸杆菌活菌剂治疗老年性阴道炎的临床疗效。方法 90例老年性阴道炎患者随机分为两组各45例,对照组阴道局部应用甲硝唑治疗,观察组在对照组治疗的基础上联合应用乳酸杆菌活菌剂,疗程均为10 d。比较两组患者起效时间、治疗有效率、复发率及治疗前后阴道健康评分。结果观察组治疗总有效率为93.3%,明显高于对照组的80.0%,观察组复发率为20.0%,明显低于对照组的42.2%,差异均有统计学意义(P<0.05);观察组起效时间平均为(4.2±1.3)d,明显短于对照组的(7.4±2.5)d,差异有统计学意义(P<0.05);治疗后两组患者阴道健康评分均较治疗前显著提高,且观察组分值高于对照组,差异有统计学意义(P<0.05)。结论甲硝唑联合乳酸杆菌活菌制剂治疗老年性阴道炎可缩短起效时间、降低复发率、更好地改善阴道局部症状、提高患者的生活质量。
Objective To investigate the effect of live lactobacillus bacterium in the treatment of senile vaginitis. Methods Ninety patients with senile vaginitis were randomly divided into two groups. The control group was treated by local application of metronidazole in vagina, and the observation group was given live lactobacillus bacterium additionally. And then the effective rate, the relapse rate and vaginal health score before and after treatment were compared between the two groups. Results The total effective rate in the observation group was 93.3%, which was significantly higher than that in the control group with 80.0%. The relapse rate in the observation group was 20.0%,which was significantly lower than that in the control group with 42.2%（P〈0.05）. The average onset time in observation group was（4.2 ± 1.3） d, which was significantly shorter than that in the control group（P〈0.05）. After treatment,the vaginal health scores were improved significantly compared with those before treatment in the two groups, and the score was higher in the observation group than that in the control group with a statistically significant difference（P〈0.05）. Conclusion Live lactobacillus bacterium combined with metronidazole in the treatment of senile vaginitis can shorten the onset time, reduce the relapse rate, and improve the vaginal symptoms and the quality of life.
出处
《海南医学》
CAS
2015年第1期131-133,共3页
Hainan Medical Journal
关键词
老年性阴道炎
乳酸杆菌活菌剂
甲硝唑
微生态环境
Senile vaginitis
Live lactobacillus bacterium
Metronidazole
Microbial environment
