摘要
目的分析女性乳腺密度的构成与生理、生育因素及乳腺癌之间相关性。方法选取接受全数字乳腺X射线摄影检查且临床资料完整的当地女性5 006例,以ACR BIRADS标准,依据乳腺X射线摄影结果评价乳腺腺体密度类型,乳腺癌以病理诊断为标准。按不同年龄、生育特征因素分组,分析其与乳腺密度构成及乳腺癌之间相关性。结果 5 006例中受检查年龄(44.22±8.09)岁,中位年龄43岁。乳腺密度构成为脂肪型256例(5.11%),少量型726例(14.51%),多量型3 719例(74.29%),致密型305例(6.09%)。乳腺密度与年龄、哺乳史、流产史、绝经年龄、绝育手术有相关性,与初潮年龄、初产年龄、服用雌激素无相关性。病理证实乳腺癌184例,其乳腺密度构成为脂肪型26例(14.13%),少量型66例(35.87%),多量型91例(49.46%),致密型1例(0.54%)。乳腺癌患者乳腺密度与年龄、绝经年龄、服用雌激素有相关性,与初潮年龄、初产年龄、哺乳史、流产史、绝育手术无相关性。结论年龄、哺乳史、流产史、绝经年龄、是否做过绝育手术是影响女性乳腺密度的重要因素,绝经期前后女性以及较低乳腺密度类型女性患乳腺癌风险更突出。
Objective It is to analyze the relevance between the structure of female breast density and physiology, repro-ductive characteristics and breast cancer.Methods 5006 cases of local women with complete data whom had accepted digital breast X-ray angiography were selected.ACR BI-RADS was used as standard to evaluate mammary gland density type.Be-sides, breast cancer was diagnosed on the basis of pathological diagnosis.In the study, all data was divided according to phys-iology and reproductive characteristics, and the composing and correlation between breast cancer and breast density was ana-lyzed.Results The average age was 44.22 ±8.09 and median age was 43.Constitution of the mammary gland density in 5 006：lard type 256（5.11%）, small type 726（14.51%）, quantity type 3719（74.29%）, and density type 305（6.09%）.There was statistically significant difference between breast density and age, lactation history, history of abortion, menopause age, sterilization etc（P〈0.01）, while there was no statistically significant difference between breast density and menarche age, first delivery, whether take strogen etc（P＆gt;0.05）.Pathology confirmed breast cancer 184 cases, constitution of the mammary gland density：lard type 26（14.13%）, small type 66（35.87%）, quantity type 91（49.46%）and density type 1（0.54%）. Significant statistically difference was found between mammary gland density and age, menopause age, whether take strogen etc（P〈0.01）.However, there was no statistically significant difference between breast density and menarche age, first deliv-ery age, lactation history, history of abortion, sterilization etc（P＆gt;0.05）.Conclusion The important factors that affect female breast density showing as follows：age, lactation history, history of abortion, menopause age, whether done sterilization, nev-ertheless, age, menopause women and low density of breast could increase the risk .
出处
《现代中西医结合杂志》
CAS
2015年第5期469-471,567,共4页
Modern Journal of Integrated Traditional Chinese and Western Medicine
关键词
乳腺密度
乳腺癌
X射线摄影术
女性
相关因素
breast density
breast cancer
X-ray photography
women
related factors
