摘要
目的探讨2型糖尿病患者血清心型脂肪酸结合蛋白（H-FABP）水平与颈动脉粥样硬化的相关性。方法根据颈动脉彩色多普勒超声检测情况选取2型糖尿病患者100例，其中颈动脉正常患者50例，颈动脉粥样硬化50例，检测所有对象血中H-FABP水平及其他血脂生化指标。结果颈动脉粥样硬化组的患者血H—FABP水平显著高于颈动脉正常患者[分别为（23．70±3．56），（8．85±3．81）ng／ml]，差异有统计学意义（P〈0．05）。结论H—FABP水平与糖尿病患者发生颈动脉粥样硬化关系密切。
Objective To investigate the relationship between the heart-type fatty acid-binding protein （ H-FABP ） and the atherosclerosis .Methods One hundred patients with type 2 diabetes mellitus were detected by color Doppler with intimal-media thickness （ IMT ） measurement. Then, patients were divided into carotid artery atherosclerosis group （ n=50 ） and control group （ n=50 ） according to IMT . The levels of H-FABP in plasma were measured Results Serum H-FABP levels were significantly higher in patients with carotid artery atherosclerosis than in control subjects （ 23.70 ± 3.56 VS 8.85 ± 3.81 ng/ml ） . There were statistically significant differences between patients in carotid artery atherosclerosis group and control subjects. Conelusion There would be a close correlation between H-FABP level and atherusclerosis
出处
《浙江临床医学》
2015年第1期16-17,共2页
Zhejiang Clinical Medical Journal
关键词
心型脂肪酸结合蛋白
动脉粥样硬化
2型糖尿病
Heart-type fatty acid-binding protein Atherosclerosis Type 2 diabetes mellitus
