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MRI联合人附睾蛋白-4检测在卵巢上皮性肿瘤诊断中的价值 被引量:1

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摘要 目的:探讨MRI联合人附睾蛋白-4(HE-4)诊断卵巢上皮性肿瘤的意义。方法:回顾性分析经手术病理证实的32例卵巢良性上皮性肿瘤患者和24例恶性肿瘤患者术前MRI诊断及HE-4测定结果,并计算其敏感度、特异度、阳性预测值。结果:卵巢囊腺癌的HE-4平均值为(312.05±180.40)pmol/L,显著高于卵巢囊腺瘤的(50.3±20.1)pmol/L,差异有统计学意义(P<0.05)。卵巢浆液性囊腺癌的HE-4平均值为(308.1±160.3)pmol/L,黏液性囊腺癌为(318.6±150.2)pmol/L,两者差异无统计学意义(P>0.05)。卵巢浆液性囊腺瘤的HE-4平均值为(50.0±22.1)pmol/L,黏液性囊腺瘤为(52.0±14.6)pmol/L,两者差异无统计学意义(P>0.05)。MRI单独诊断卵巢上皮性肿瘤的敏感度(83.33%)、特异度(81.25%)、阳性预测值(76.92%)均低于单独HE-4诊断的敏感度(87.50%)、特异度(84.38%)、阳性预测值(80.76%)。MRI和HE-4联合诊断的敏感度(91.67%)、特异度(90.63%)、阳性预测值(84.62%)均高于MRI和HE-4的单独应用。结论:对卵巢上皮性肿瘤的诊断,MRI和HE-4联合应用可提高诊断准确度。
作者 朱大林 冯帆
出处 《中国中西医结合影像学杂志》 2014年第6期613-614,共2页 Chinese Imaging Journal of Integrated Traditional and Western Medicine
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