摘要
目的：探讨联合应用复方甘草酸苷片和派瑞松乳膏治疗湿疹的临床效果。方法选择2012－01～2013－12间确诊的98例湿疹患者，向患者说明不同用药方案并根据患者主观选择分组：单用复方甘草酸苷片（口服）患者48例为单药组，联合应用派瑞松乳膏（外用）和复方甘草酸苷片患者50例为联合组，评价两组疗效及不良反应。结果联合组治疗总有效率为88％，单药组为67％，两组数据间比较具有统计学差异（ P＜0.05）。联合组患者未发生不良反应，单药组患者仅1例（2.1％）主诉用药时有局部烧灼感，持续用药2 d后烧灼感消失，两组患者不良反应发生率比较无统计学意义（P＞0.05）。结论联合应用复方甘草酸苷片和派瑞松乳膏治疗湿疹具有较好的疗效和安全性，且可有效减少单纯长期应用皮质类固醇用药可能带来的副作用，值得临床推广应用。
Objective To investigate the clinical effect of the combination of glycyrrhizin tablets combined with pevisone cream on the treatment of eczema.Methods Selecting 98 patients confirmed with eczema from January , 2012 to December , 2013 , patients were grouped based on patient subjective choice：48 patients with single-use glycyrrhizin tablets （oral） were set as the monotherapy group , 50 patients with joint application pevisone cream （ topical ） and glycyrrhizin tablets were set as the joint group.The efficacy and adverse reactions of two groups were evaluated.Results The total treatment effective of the joint group was 88%, the monotherapy group was 67%, with statistical-ly significant difference （ P〈0.05 ）.Adverse reactions in patients in combination group did not occur （ 0%）.Only 1 case （ 2.1%） had local burning sensation in monotherapy group , and after 2 days′medication, burning sensation disappeared.There was no statistical signifi-cance the incidence of adverse reactions of two groups （ P〉0.05 ）.Conclusion The combination of glycyrrhizin tablets and creams to treat eczema pevisone has better efficacy and safety , and can effectively reduce the long -term use of corticosteroids alone possible side effects of medication.So it is worthy of clinical application.
出处
《黑龙江医学》
2015年第1期33-34,共2页
Heilongjiang Medical Journal
