摘要
目的:通过复方阿胶颗粒对缩宫素致大鼠痛经样反应的影响,探讨复方阿胶颗粒缓解经期痛经症状的机制。方法:观察复方阿胶颗粒对缩宫素所致的体外子宫平滑肌剧烈收缩的影响,及其对痛经痉挛的抑制作用。结果:复方阿胶颗粒显著抑制缩宫素所致的体外子宫平滑肌的收缩,明显减少痛经大鼠扭体反应次数、延长发生扭体的潜伏期。结论:复方阿胶颗粒具有缓解经期痛经时痉挛及疼痛的作用。
Objective： To explore the mechanism of fu fang e jiao ke li（FFEJ） relieve menstrual symptoms of dysmenorrheal by FFEJ on oxytocin induced dysmenorrhea-like reaction. Methods： To observe FFEJ on oxytocin induced uterine smooth muscle in vitro contrac- tion of violent, and inhibition on spasmodic dysmenorrhea. Results： FFEJ could strongly inhibit the autonomic contraction activities of free ratuterus in those uterine smooth muscle in vitro induced by oxytocin. It also could significantly decrease the torsion times and prolong the incubation period writhing. Conclusion： FFEJ can relieve spasmodic dysmenorrheal and pain.
出处
《中国药物评价》
2014年第6期338-340,共3页
Chinese Journal of Drug Evaluation
基金
山东省科技发展计划--经典中药大品种阿胶技术升级(2013G0031901)
关键词
复方阿胶颗粒
子宫平滑肌
扭体反应
痛经
Fu Fang E Jiao Ke Li
Uterine smooth muscle
Writhing response
Menorrhalgia
