摘要
术后认知功能障碍(postoperative cognitive dysfunction,POCD)是发生在手术麻醉以后的可逆性或长期存在的严重并发症,好发于老年人群。POCD需要与痴呆和术后谵妄相鉴别。近年来,许多危险因素被认为与POCD的发生有关,然而其确切的病因仍未知。本文就POCD诊断、发病机制和治疗方面的进展进行综述。
Postoperative cognitive dysfunction（ POCD） is a severe transient or long-term complication after surgical procedures and anesthesia,especially in the elderly population. POCD should be distinguished from dementia or acute postoperative delirium. M ultiple risk factors have been identified over the last decade. However,the exact etiology is still unknown. This article reviews the recent progress concerning diagnosis,potential mechanisms and treatment of POCD.
出处
《同济大学学报（医学版）》
CAS
2014年第5期119-123,共5页
Journal of Tongji University(Medical Science)
基金
上海市浦东新区卫生系统重点专科(PWZz2013-17)
上海市浦东新区科委科技发展创新基金(PKJ2011-Y37)
关键词
术后认知功能障碍
谵妄
痴呆
神经炎症
凋亡
突触
postoperative cognitive dysfunction
delirium
dementia
neuroinflammation
apoptosis
synapse
