摘要
目的 探讨高压氧（hyperbaric oxygen,HBO）综合治疗对不完全颈髓损伤术后恢复的影响.方法 分析我院骨科2010年6月至2012年6月收治的78例因外伤引起的不完全颈髓损伤患者的临床资料,所有患者均有完整随访资料,年龄、性别、受伤部位、病情等方面差异无统计学意义,且所有患者在受伤2周内均行神经减压内固定术.经患者知情同意,并经医院伦理委员会批准,将患者分为HBO治疗组（HBO组）40例和非HBO治疗组（NHBO组）38例,术后NHBO组只采用常规治疗,HBO组在常规治疗的基础上辅以HBO治疗,于治疗前、治疗1个月、治疗3个月、治疗6个月及术后1年分别采用美国脊髓损伤协会（ASIA）评分及Barthel指数对患者脊髓功能及日常生活活动能力（ADL）进行评定.结果 HBO组和NHBO组总有效率分别为90.0％、78.9％,2组差异有统计学意义（P＜0.05）;2组间ASIA评分及Barthel指数在治疗1个月、治疗3个月、治疗6个月及治疗1年的差异均有统计学意义（P＜0.05）,HBO组疗效优于NHBO组;恢复最明显的时期为术后第1个月,在治疗1个月后,HBO组及NHBO组患者ASIA感觉、运动功能评分及Barthel指数评分均较治疗前明显改善,且HBO组评分显著优于NHBO组,差异有统计学意义（P＜0.01）.结论 HBO综合治疗不完全颈髓损伤是安全、有效的;术后3个月内治疗持续的时间越长效果越好;术后前3个月脊髓功能的恢复最明显.正确的HBO治疗能有效促进脊髓功能恢复,降低致残率,明显提高患者的生活质量.
Objective To investigate the effects of comprehensive hyperbaric oxygen （HBO） therapy on the recovery of patients following surgery of incomplete cervical spinal injury.Methods A retrospective analysis was made on the clinical data of 78 cases of incomplete cervical spinal injury by trauma collected from the medical file of our hospital from June 2010 to June 2012.All the patients had complete follow-up medical data,and no statistical significance could be noted in age,gender,injury sites,seriousness of injury etc.In addition,all the patients underwent nerve decompression and internal fixation within 2 weeks after injury.With the knowledge and consent of the patients and following approval by the Hospital Ethics Committee,the patients were divided into the HBO group （40 cases） and non-HBO（NHBO）group （38 cases）.Following surgery,the patients in the NHBO group were treated with only routine treatment,while the patients in the HBO group received HBO therapy in addition to routine treatment.American Spinal Cord Injury Association （ASIA） Scores and Barthel＇s Index （BI） were respectively used to evaluate the spinal cord function and their daily life activity,before treatment,1 month and 3 months after treatment,6 months and 1 year after surgery.Results Total effective rates for the HBO group and the NHBO group were 90.0％ and 78.9％,with statistical significance,when comparisons were made between the 2 groups （P ＜ 0.05）.Following 1 month and 3 months of treatment,and after 6 months and l year of surgery,statistical significance could be noted in the scores of ASIA and BI between the 2 groups （P ＜ 0.05）,with the therapeutic effect of the HBO group being superior to that of the NHBO group.Recovery was most obvious in the first month after surgery.One month after surgery,ASIA scores,motor function scores and Barthel scores for both the HBO group and the NHBO group were all significantly higher,as compared with those before treatment,with the scores of the HBO group being significant
出处
《中华航海医学与高气压医学杂志》
CAS
CSCD
北大核心
2014年第5期312-316,共5页
Chinese Journal of Nautical Medicine and Hyperbaric Medicine
关键词
高压氧
颈髓损伤
临床疗效
Hyperbaric oxygen
Cervical spinal injury
Clinical effect
