摘要
目的观察前颞叶切除术和选择性海马、杏仁核切除术对颞叶内侧癫痫的发作控制效果是否有差别。方法 2009年1月至2010年12月在我科行前颞叶切除术的67例颞叶内侧患者为A组;2011年6月至2013年5月在我科行选择性海马、杏仁核切除术的46例颞叶内侧患者为B组;统计分析两组术后1年发作控制为Engel I-II级和Engel III-IV级的人数。结果 A组Engel I-II级56例(83.58%),Engel III-IV级11例(16.42%);B组Engel I-II级40例(86.95%),Engel III-IV级6例(13.05%)。经χ2检验两组术后对MTLE发作的控制率无统计学差异,χ2=0.243,P>0.05。结论前颞叶切除术和选择性海马、杏仁核切除术对颞叶内侧癫痫发作都能获得良好的控制,两者疗效无明显差异。
Objective To observe if there is difference between the outcomes of seizure control of mesial temporal lobe epilepsy（MTLE）after anterior temporal lobectomy（ATL）and selective amygdalohippocampectomy（SAH）.Methods 67 MTLE cases experienced ATL from Jan 2009 to Dec 2010（group A）and 46 MTLE cases experienced SAH from Jun 2011 to May2013（group B）in our epilepsy center.The cases of Engel I-II and Engel III-IV（1year after operation）of two groups were statistically analyzed.Results 56cases（83.58%）in group A and40cases（86.95%）in group B were Engel I-II.11cases（16.42%）in group A and 6cases（13.05%）in group B were Engel III-IV.There was no statistical difference between the outcomes of two groups throughχ2 test（χ2=0.243,P〉0.05）.Conclusion ATL and SAH both had satisfactory outcomes in seizure control for MTLE.There was no difference between the outcomes of two operation style.
出处
《立体定向和功能性神经外科杂志》
2014年第5期261-264,共4页
Chinese Journal of Stereotactic and Functional Neurosurgery
基金
国家重点基础研究发展计划项目(973计划
编号:2012CB720704)
清华大学自主创新课题项目(编号:2011Z01015)
关键词
颞叶内侧癫痫
前颞叶切除术
选择性海马杏仁核切除术
发作控制
Mesial temporal lobe epilepsy
Anterior temporal lobectomy
Selective amyg-dalohippocampectomy
Seizure control
