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WHO(2014)女性生殖器官肿瘤分类解读 被引量:20

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摘要 新版WHO女性生殖器官肿瘤分类在今年上半年问世。新版卵巢肿瘤分类继承了Scully的原分类框架,主要变化是将卵巢浆液性以外类型的交界性肿瘤改称为"非典型增生性肿瘤",可用"交界性肿瘤/非典型增生性肿瘤"表达;将浆液性交界性肿瘤的微乳头变型称为"SBT,微乳头变型/非浸润性低级别浆液性癌",其ICD-O由1改为2(原位癌);将卵巢浆液性癌依据预后和分子遗传的不同,分为2个级别:分别是来源于卵巢交界性肿瘤的低级别浆液性癌和主要来源于输卵管的浆液性癌。在子宫内膜癌前驱病变方面整合了传统分类和Mutter的EIN分类,即子宫内膜非典型增生与子宫内膜上皮内瘤(EIN)等同,以"非典型增生/子宫内膜样上皮内瘤"表达,主要问题仍是如何判断"非典型性";另外,新版根据病源学类型和临床的相关性,将宫颈癌前驱病变由传统的3级分类改为高、低2级病变,其重点是CIN2应尽可能划归为CIN1或CIN3,分类时可参考p16及Ki-67的检测结果。
出处 《诊断病理学杂志》 CSCD 北大核心 2014年第12期725-729,共5页 Chinese Journal of Diagnostic Pathology
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