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Toll样受体在结肠癌发生发展中作用的研究进展

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摘要 Toll样受体（Toll-like receptors,TLRs）是天然免疫中重要的模式识别受体（pattern recognition receptor）,在启动和调节天然免疫及获得性免疫中起到重要作用。越来越多的研究认为TLRs信号与肿瘤的生物学行为相关,它能通过免疫逃逸、免疫耐受、抵制凋亡等促进肿瘤细胞存活、增殖、迁移,从而促进肿瘤发生发展。
作者 肖朝朝 吴发明
机构地区 三峡大学医学院 三峡大学第三临床医学院 葛洲坝中心医院消化内科
出处 《广东医学》 CAS CSCD 北大核心 2014年第24期3924-3926,共3页 Guangdong Medical Journal
关键词 肿瘤发生发展 TOLL样受体 结肠癌 模式识别受体 天然免疫 获得性免疫 生物学行为 TLRS
分类号 R73-31 [医药卫生—肿瘤]
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参考文献25

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广东医学
2014年 第24期

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