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无创正压通气对OSAHS患者脑血流的影响 被引量:3

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摘要 目的探讨无创正压通气对阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的脑血流的影响。方法 26例初治OSAHS患者(A组),11例同期体检者作为对照(B组)。受试者均进行多导睡眠图(PSG)监测,A组确诊OSAHS,B组排除OSAHS。采用经颅多普勒超声(TCD)检查测定A组治疗前和持续无创正压通气6个月和12个月时的脑血流和脑血管狭窄情况,分析脑血流减慢和脑血管狭窄改善病例,记录脑血管事件的发生情况。结果与治疗前比较,A组治疗6个月和12个月脑血流速度减慢的病例明显减少(42.3%和30.8%vs.84.6%)(P<0.01),脑血管狭窄病例亦明显减少(26.9%和19.2%vs.57.7%)(P<0.05)。A组26例患者,治疗期间均无脑梗死、脑出血等相关脑血管事件的发生。结论无创正压通气有助于改善OSAHS患者的脑血流,预防脑血管事件的发生。
作者 陶杨 左志通
出处 《江苏医药》 CAS 北大核心 2014年第23期2913-2914,共2页 Jiangsu Medical Journal
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参考文献9

  • 1阻塞性睡眠呼吸暂停低通气综合征诊治指南(2011年修订版)[J].柳州医学,2012,25(3):162-165. 被引量:88
  • 2Benbir G, Karadeniz D. A pilot study of the effects of non- invasive mechanical ventilation on the prognosis of isehemicce- rebrovascular events in patients with obstructive sleep apnea syndrome[J]. Neurol Sci, 2012,33 (4) : 811-818. 被引量:1
  • 3祁风,韦朝霞,刘祖佑,余科.阻塞性睡眠呼吸暂停综合征患者脑血流动力学研究[J].中华全科医学,2009,7(5):454-455. 被引量:9
  • 4Yadav SK, Kumar R, Macey PM, et al. Regional cerebral blood flow alterations in obstructive sleep apnea[J]. Neurosci Lett, 2013,555:159-164. 被引量:1
  • 5Kohler M, Stradling JR. Mechanisms of vascular damage in obstructive sleep apnea[J]. Nat Rev Cardiol, 2010,7 (12) : 677- 685. 被引量:1
  • 6Rae C, Bartlett DJ, Yang Q, et al. Dynamic changes in brain bioenergetics during obstructive sleep apnea[J]. J Cereb Blood Flow Metab, 2009,29(8) : 1421-1428. 被引量:1
  • 7Foster GE, Hanly PJ,Ostrowski M, et al. Effects of continuous positive airway pressure on cerebral vascular response to hypoxia in patients with obstructive sleep apnea[J]. Am J Respir Crit Care Med, 2007,175 (7) : 720-725. 被引量:1
  • 8J imnez Caballero PE, Coloma Navarro R, Ayo Martin O, et al. Cerebral hemodynamic changes in obstructive sleep apnea syn- drome after continuous positive airway pressure treatment[J]. Sleep Breath, 2013,17 (3) : 1103-1108. 被引量:1
  • 9Yiallourou TI, Odier C, Heinzer R, et al. The effect of conti- nuous positive airway pressure on total cerebral blood flow in healthy awake volunteer[J]. Sleep Breath, 2013, 17 (1): 289- 296. 被引量:1

二级参考文献11

  • 1祁风,徐恩,陆雪芬,陈秀梅,谢海峰.缺血性卒中大脑中动脉狭窄患者脑血管反应能力的研究[J].中华超声影像学杂志,2004,13(6):470-471. 被引量:9
  • 2何权瀛.阻塞性睡眠呼吸暂停低通气综合征对心脑血管的损害[J].中华全科医师杂志,2005,4(4):207-208. 被引量:26
  • 3Lavie P, Lavie L. Cardiovascular morbidity and mortality in obstructive sleep apnea [J]. Curr Pharm Des,2008,14 ( 32 ) :3466-3473. 被引量:1
  • 4Ozdemir O,Beletsky V, Hachinski V,et al. Cerebrovascular events on awakening, patent foramen ovale and obstructive sleep apnea syndrome [ J ]. J Neurol Sci,2008,268 ( 1-2 ) : 193-194. 被引量:1
  • 5Yaggi HK,Concato J, Keman WN,et al. Obstructive sleep apnea as a risk factor for stroke and death[J].N Engl J Med, 2005,353 ( 19 ) : 2034-2041. 被引量:1
  • 6Lattimore L, David S. Obstructive sleep apnea and cardiovascular disease[ J]. J Am Coll Cardiol,2003,41 : 1429-1437. 被引量:1
  • 7Wierzbicka A, Rola R,Wichniak A, et al. The incidence of sleep apnea in patients with stroke or transient ischemic attack[J]. J Physiol Pharmacol, 2006,57 ( 4 ) : 385-390. 被引量:1
  • 8Mohsenin V. Sleep-related breathing disorders and risk of stroke [ J ]. Stroke ,2001,32 ( 6 ) : 1271-1278. 被引量:1
  • 9Beelke M,Angeli S,Del Sette M, et al. Prevalence of patent foramen ovale in subjects with obstructive sleep apnea:a transcranial Doppler ultrasound study [ J ]. Sleep Med ,2003,4 ( 3 ) :219-223. 被引量:1
  • 10Gibson G J. Sleep disordered breathing and the outcome of stroke [ J ]. Thorax,2004,59 : 361-363. 被引量:1

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