摘要
目的 研究牙周病与妊娠期糖尿病的相关性,探讨牙周炎对妊娠期糖尿病血清C-反应蛋白的影响。方法 选择24~28周孕妇中,患有妊娠期糖尿病孕妇100例纳入试验组,身体健康孕妇100例作为对照组,检查其牙周健康指数,其中包括牙龈指数、龈沟出血指数、附着丧失水平、牙周袋探诊深度,统计分析两组差别。同时在试验组孕妇中选取伴牙周炎和牙周健康的孕妇各30例,检测其血清C-反应蛋白的含量,进行统计学分析。结果 除牙周探诊深度外,两组孕妇的其他牙周健康指数均的差异有统计学意义（P〈0.05）,试验组牙周炎孕妇的血清C-反应蛋白水平显著高于同组牙周健康的孕妇（P〈0.05）。结论 牙周病与妊娠期糖尿病具有相关性,牙周炎症可能是妊娠期糖尿病的危险因素之一。
Objective To explore the correlation between periodontal disease and gestational diabetes mellitus（GDM） and determine whether or not periodontal disease influences the content of the serum C-reactive protein of GDM patients. Methods A case-control study was conducted consisting of 100 pregnant women with GDM and 100 pregnant women without GDM at 24 to 28 weeks of pregnancy. Periodontal parameters, including gingival index（GI）, sulcus bleeding index（SBl）, attachment level（AL）, and probing depth（PD）, were examined by a calibrated dentist. A student t-test was employed to analyze the difference between the two. Meanwhile, 30 cases of periodontitis and 30 cases of healthy periodontal situation were selected from the pregnant women with GDM. The content of C-reactive protein was examined and statistically analyzed. Results Aside from the periodontal probing depth, other periodontal health indexes significantly differed between the two groups（P〈0.05）. The serum C-reactive protein level of the pregnant women with both GDM and periodontitis was obviously higher than that the pregnant women with healthy periodontal situation（P〈0.05）. Conclusion Periodontal diseases correlate with gestational diabetes mellitus, and periodontitis may be a risk factor of gestational diabetes mellitus.
出处
《国际口腔医学杂志》
CAS
北大核心
2015年第1期19-21,共3页
International Journal of Stomatology
基金
深圳市科技局计划项目(200903118)
关键词
牙周病
妊娠期糖尿病
C-反应蛋白
periodontal diseases
gestational diabetes mellitus
C-reactive protein
