摘要
目的了解我国妊娠合并糖尿病的研究现状,明确进一步的研究方向。方法对CNKI中国期刊全文数据库进行全部检索,选择中国中文期刊有关"妊娠合并糖尿病"的论著类文献。按既定纳入和排除标准进行文献选择。选中的文献由专人逐篇阅读,并进行数据录入和分析。结果共检索到符合要求的文献515篇,文章发表数量逐年增加,自1981年开始,1999年全年10篇,2003年全年51篇,2006年全年增加到133篇。515篇文献中基础研究131篇(25.4%),临床研究384篇(74.6%)。基础研究的内容主要有病因和发病机制(71篇,54.2%)、对妊娠结局的影响机制(21篇,16.0%)、实验室检测结果报告(19篇,14.5%)。临床研究的内容主要有母儿结局报告(196篇,51.0%)、临床处理后的母儿结局分析(88篇,22.9%)、妊娠期糖尿病的筛查和诊断(56篇,14.6%)、妊娠期糖尿病高危因素(25篇,6.5%)、远期随访(9篇,2.3%)。全部文献中多中心研究报告仅有5篇,分别来自北京、天津和上海的3个多中心研究。结论在过去的近30年里,国内对妊娠合并糖尿病研究的重视程度明显增加,基础研究明显少于临床研究。临床研究中简单临床结局报告过多,创新性研究少,前瞻性、多中心、大规模临床研究欠缺。
Objective To understand the current situation of the studies on pregnancy associated with diabetes mellitus （GDM） in China and to find the direction of further studies. Methods The CNKI Chinese full -text literature database was searched for all original and experimental research articles on pregnancy complicated by diabetes published in Chinese. Articles were selected according to the inclusion criteria. Those articles included in this study were reviewed by a specialized person and data were collected and analyzed. Results Totally 515 articles were included in this study. The quantity of publications increased year by year since 1981 ： 10 in 1999, 51 in 2003 and 133 in 2006）. In all 515 articles, 131 were of basic study （25. 4% ） and 384 were of clinical study （74. 6% ）. The major contents in basic study were on the etiology and pathogenesis （71 articles, 54. 2% ）, the mechanism of influence on pregnancy outcome （21, 16. 0% ）, and laboratory results reports （19, 14. 5% ）. The main contents of the clinical study were on the fetomaternal outcome reports （ 196, 51. 0% ）, analysis of the fetomaternal outcome after a certain clinical treatment （88, 22. 9% ）, screening and diagnosis of GDM （56, 14. 6% ） , risk factors for GDM （ 25, 6. 5% ） and long - term follow up （ 9, 2. 3% ）. Five papers in all were multi - centered research report from Beijing, Tianjin and Shanghai, respectively. Conclusion The study of GDM has drawn remarkable attentions during the past 30 years at home. However, the basic studies are obvious less than the clinical studies. And the clinical studies are more in clinical outcome reports and less in creativity, and prospective multi - centered and large scaled clinical trial.
出处
《中国全科医学》
CAS
CSCD
2008年第7期547-550,共4页
Chinese General Practice
关键词
糖尿病
妊娠
文献
中文
Diabetes, pregnancy
Literature, Chinese
