摘要
测定２９例糖尿病患者及２３例正常孕妇羊水中的Ｃ肽，并分析了羊水Ｃ肽水平与糖尿病分期、血糖控制效果的关系。结果，羊水Ｃ肽平均值：糖尿病组１．９±１．５μｇ／Ｌ，正常对照组０．９±０．５μｇ／Ｌ，两组比较Ｐ＜０．０１。并且羊水Ｃ肽与糖尿病孕期血糖控制程度有关，而与糖尿病分期无关，所以不能单独依靠糖尿病病情程度来推断胎儿宫内受累情况。也表明严格控制孕期血糖至正常范围可减少胎儿高胰岛素血症发生，避免胎儿宫内过度增长及新生儿合并症发生。由于羊水Ｃ肽水平与平均空腹血糖无显著相关性，单纯依靠空腹血糖水平不能准确反映胎儿宫内受累程度。
prospective study on amniotic fluid C-peptide(AFCP) was
made in 29 women with diabetic preg-nancy and 23 non-diabetic control subjects. The
meanconcentrations of AFCP were found to be significantlyhigher in diabetic pregnancy than in
non-diabeticpregnancy (P<0.01) (diabetic group AFCP 1.89±1 .53ng / ml; control gsoup 0.88 ±
0.51ng / ml). AFCPlevels were related to the degree of blood glucose con-trol during pregnancy
and not to diabeticclassification. The results show that fetalhyperinsulinemia reduced in these
women that theachieved metabolic control of maternal blood glucoselevels approached normal
values. A higher neonatalcomplications occurred while AFCP was over1.68ng / ml.
出处
《中华医学杂志》
CAS
CSCD
北大核心
1994年第5期296-298,共3页
National Medical Journal of China
关键词
妊娠
糖尿病
羊水
肽
Pregnancy Diabetes Amnioticfluid C-peptide
