期刊文献+

沙利度胺联合干扰素治疗12例复发难治性套细胞淋巴瘤 被引量:12

Thalidomide combined with interferon in 12 cases of relapsed or refractory mantle cell lymphoma
原文传递
导出
摘要 套细胞淋巴瘤(MCL)是一种恶性程度高、病理组织学形态多样、预后不良的非霍奇金淋巴瘤(NHL),其目前尚无标准的治疗方案,尽管随着靶向药物CD20单抗、硼替佐米的应用,以及大剂量化疗、造血干细胞移植水平的提高,其缓解率及总体生存率有所提高,但本病仍为一种不可治愈的疾病,特别是对复发难治性MCL患者,其生存期更短,且本病多见于老年人,常伴随脏器功能紊乱,因此有必要探索新的安全有效、价格低廉的治疗方案.我们应用沙利度胺联合干扰素(IFN)治疗12例难治性MCL患者,取得了较好疗效,现报道如下。
出处 《中华血液学杂志》 CAS CSCD 北大核心 2014年第11期1013-1015,共3页 Chinese Journal of Hematology
基金 国家自然科学基金(81170520、81000921) 河南省卫生厅科研课题(2011010014)
  • 相关文献

参考文献15

  • 1孙燕,石远凯.临床肿瘤内科手册[M].5版.北京:人民卫生出版社,2011:135-146. 被引量:21
  • 2Vasvari GP, Dyckhoff G, Kashfi F, et al. Combination of thalido- mide and cisplatin in an head and neck squamous cell carcino- mas model results in an enhanced antiangiogenic activity in vivo [J].Int J Cancer, 2007, 121 (8):1697-1704. 被引量:1
  • 3Haslett PA, Roche P, Butlin CR, et al. Effective treatment of erythema nodosum leprosum with thalidomide is associated with immune stimulation [ J]. J Infect Dis, 2005, 192 (12) :2045- 2053. 被引量:1
  • 4Richardson P, Hidershima T, Anderson K. Thalidomide: emerg- ing role in cancer medicine [J]. Annu Rev Med, 2002, 53: 629- 657. 被引量:1
  • 5Haslett PA, Corral LG, Albert M, et al. Thalidomide costimu- lates primary human T lymphocytes, preferentially inducing pro- liferation, cytokine production, and cytotoxic responses in the CD8+ subset[J]. J Exp Med, 1998, 187(11):1885-1892. 被引量:1
  • 6Davies FE, Raje N, Hideshima T, et al. Thalidomide and immu- nomodulatory derivatives augment natural killer cell cytotoxici- ty in multiple myelomal J]. Blood, 2001, 98( 1 ):210-216. 被引量:1
  • 7Damaj G, Lefrare F, Delarue R, et al. Thalidomide therapy induces response in relapsed mantle cell lymphoma [J]. Leukemia, 2003, 17(9) : 1914-1915. 被引量:1
  • 8Gottardi M, Danesin C, Canal F, et al. Complete remission induced by thalidomide in a case of angioim-m unoblastic T cell lymphoma refractory to autologous stem cell transplantation[J]. Leuk Lymphoma, 2008, 49(9) : 1836-1838. 被引量:1
  • 9Sacchi S, Federico M, Vitolo U, et al. Clinical activity and safety of combination immunotherapy with IFN-alpha 2a and Rittux- imab in patients with relapsed low grade non-Hodgkin' s lym- phoma[J]. Haematologica, 2001, 86(9): 951-958. 被引量:1
  • 10Armitage JO, Coiffier B. Activity of interferon-a in relapsed patients with diffuse large B-cell and peripheral T-cell non- Hodgkin' s lymphoma[J]. Ann Oncol, 2000, 11 (3):359-361. 被引量:1

二级参考文献18

  • 1Mesa RA, Steensma DP, Pardanani A, et al. A phase 2 trial of combination low dose thalidomide and prednisone for the treatment of myelofibrosis with myeloimetaplasia. J Blood, 2003, 101:2534. 被引量:1
  • 2Mesa RA, Hanson CA, Rajkumar SV, et al. Evaluation and clinical correlations of bone marrow angiogenesis in myelofibrosis with myeloid metaplasia. J Blood, 2000, 96: 3374. 被引量:1
  • 3Vacca A, Ribatti D, Presta M, et al. Bone marrow neovascular ization plasema cell angiogenic potential and matrix metalloproteinase-2 secretion parallel progression of human multiplemyeloma.J Blood, 1999, 13= 3064. 被引量:1
  • 4Beliamy W, Richter L , Frutigar Y, et al. Expression of vascular endothelial growth factor and its receptor in hematological malignancies. J Cancer Res, 1999, 59: 728. 被引量:1
  • 5Piccaluga PP, Visani G, Pileri SA, et al. Clinical efficacy and antiangiogenic activity of thalidomide in myelofibrosis with myeloid metaplasia: a pilot study Leukemia,2002,16:1609. 被引量:1
  • 6Giovanni B, Michelle E, Letizia C, et al. Thalidomide in myelo-fibrosis with myeloidmetaplasia: apooled 2 analysis of individual patient data from five studies. Leuk Lymphoma, 2002,43:2301. 被引量:1
  • 7List AF, Kummet TD, Kerr DM. Acute myelofibrosis response to recombinant human interferon alpha-2a. J Leuk Res, 1990, 14:321. 被引量:1
  • 8Wilson EA, Jobanputra S, Jackson R, et al. Response to thalido- mide in chemotherapy-resistant mantle cell lymphoma: a case report. Br J Haematol, 2002, 119 : 128-130. 被引量:1
  • 9Damaj G, Lefrere F, Delarue R, et al. Thalidomide therapy induces response in relapsed mande cell lymphoma. Leukemia, 2003,17:1914-1915. 被引量:1
  • 10Kaufmann H, Raderer M, Wohrer S, et al. Antitumor activity of rituximab plus thalidomide in patients with relapsed/refractory mantle cell lymphoma. Blood, 2004, 104 : 2269-2271. 被引量:1

共引文献28

同被引文献141

引证文献12

二级引证文献48

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部