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吉西他滨、奥沙利铂联合甲强龙治疗复发或难治非霍奇金淋巴瘤疗效观察 被引量:1

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摘要 目的:分析吉西他滨、奥沙利铂、甲强龙联合化疗方案治疗复发或难治非霍奇金淋巴瘤(non-Hodgkin's lymphoma,NHL)的疗效及毒副反应。方法:全组83例复发或者难治NHL患者接受了至2个周期以上的化疗。方案:吉西他滨1000 mg/m^2,d1,8;奥沙利铂130 mg/m^2,d1;甲强龙500 mg,d1~5;以上药物均静脉滴注,每21~28 d为1个周期,完成2个周期化疗后评价疗效,完成1个周期化疗后评价毒副反应。结果:CR7例(8.4%),PR31例(37.3%),SD38例(45.8%),PD 7例(8.4%),总有效率(ORR)为45.7%;9例B症状患者B症状消失,6例症状明显改善。化疗的主要不良反应是骨髓抑制及神经毒性,全组无化疗相关性死亡。结论:吉西他滨、奥沙利铂、甲强龙联合化疗方案治疗复发或难治NHL有较好的近期疗效,且患者耐受性好,是值得推荐的一个挽救方案。
出处 《新疆医学》 2013年第5期45-47,共3页 Xinjiang Medical Journal
基金 新疆维吾尔自治区自然科学基金项目(2012211A045)
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参考文献11

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