摘要
目的:分析黄芪注射液对老年高血压患者血小板参数、氧化应激指标的影响。方法:选择郑州大学第一附属医院收治的70例老年高血压患者作为研究对象,随机分为观察组和对照组,各35例。对照组患者给予常规治疗,观察组患者在常规治疗基础上给予黄芪注射液治疗,观察两组患者的血小板参数及氧化应激指标(血清NO、SOD、NOS、MDA)的变化情况。结果:1观察组治疗2周后测定的PDW、MPV、PLCR、PCT水平均明显低于对照组,差异具有统计学意义(P<0.05)。2观察组患者治疗2周后的NO、NOS、SOD水平明显高于对照组,而MDA水平明显低于对照组,差异具有统计学意义(P<0.05)。结论:黄芪注射液有助于改善老年高血压患者血小板参数和氧化应激指标,有利于改善机体综合状态,值得推广使用。
Objective：To investigate the influence of astragalus injection on platelet parameters and oxidative stress indices of elderly patients with hypertension .Methods：70 patients with hyperten-sion in the First Affiliated Hospital of Zhengzhou University were selected and divided into control group and observation group , 35 cases in each .The control group was given conventional treat-ment, the observation group was given astragalus injection on the basis of conventional treatment . The platelet parameters and oxidative stress indices （ NO, SOD, NOS, MDA） of two groups were analyzed .Results：①After 2 weeks of treatment , the levels of PDW, MPV, PLCR, PCT in obser-vation group were significantly lower than control group （ P〈0 .05 ） .②After 2 weeks of treat-ment, the levels of NO, NOS and SOD in observation group were significantly higher than control group, while the level of MDA was significantly lower than control group （P〈0.05）.Conclu-sion：Astragalus injection could improve the levels of platelet parameters and oxidative stress indi-ces of elderly patients with hypertension , which is beneficial to improve the body＇s comprehensive state.It deserves the clinical expansion .
出处
《河南医学研究》
CAS
2014年第9期14-16,共3页
Henan Medical Research
关键词
老年
高血压
黄芪注射液
血小板参数
氧化应激指标
elderly hypertension astragalus injection platelet parameters oxidative stress indi-ces
