摘要
目的建立吹扫捕集-气相色谱质谱联用法测定医疗用品中环氧乙烷残留量的方法。方法采用气相色谱质谱联用仪,对医疗用品中残留环氧乙烷进行定量分析。结果所建立的方法可测定环氧乙烷浓度范围在0.2-4.0μg/ml,能用于医疗用品残留环氧乙烷的测定。标准曲线线性关系良好,相关系数r为0.9998;相对标准偏差为0.7%-1.9%,加标回收率为93.2%-98.6%;按取样5.00 g,定容至50 ml计算,最低检出限为0.02μg/g。结论所建立的吹扫捕集-气相色谱质谱联用法,具有灵敏度高、精密度和准确度好等优点,适用于医疗用品中环氧乙烷残留量的检测。
Objective To develop method for the determination of etyhlene oxide residues in medical supplies by Purge - trap GC - MS. Methods The gas chromatography mass spectrometry for quantitative analysis of etyhlene oxide residues in medical supplies was used. Results The linear ranges of determination for etyhlene oxide was 0.2 - 4.0 μg/ml （ r = 0.9998）. The relative standard deviation for etyhlene oxide was 0.7 % - 1.9 %. The recovery of sample for Etyhlene oxide was 93.2 % - 98.6 %. When sampling 5 g setting the volume to 50 ml, the limit of detection was 0.02 μg/g. Conclusion The method has the advantages of high sensitivity, good precision and accuracy, which can be better adapt to the determination of etyhlene oxide residues in medical supplies.
出处
《中国消毒学杂志》
CAS
北大核心
2014年第10期1047-1049,共3页
Chinese Journal of Disinfection
关键词
医疗用品
环氧乙烷残留
气相色谱质谱联用法
检测
medical supplies
etyhlene oxide residue
gas - chromatography mass spectrometry
determination
