摘要
目的:探讨全胃切除联合脾切除术治疗进展期胃癌的有效性和安全性。方法:回顾性分析2008—2013年进展期胃癌50例患者的临床资料。胃癌全胃切除手术34例(对照组),全胃切除联合脾切除术16例(观察组),观察比较两组的手术情况、转移淋巴结分布情况和1、3、5年生存率。结果:观察组并发症发生率明显高于对照组(31.3%vs 5.9%,P<0.05);观察组1年生存率明显低于对照组(37.5%vs64.7%,P<0.05);两组的3年和5年并发症发生率和生存率比较差异无统计学意义(P>0.05);观察组No.10和11组转移淋巴结(6/23.1%)明显高于对照组(4/8.2%,P<0.05)。结论:全胃切除联合脾切除不能提高进展期胃癌的生存率;无脾转移或10、11组淋巴结转移的进展期胃癌患者应谨慎选择联合脾切除术。
Objective： To investigate the efficacy and safety of advanced gastric cancer treated by total gastrectomy combined splenectomy. Methods： Retrospectively analyzed the clinical data of 50 patients with advanced gastric cancer from February 2008 to February 2013, including total gas- trectomy 34 cases （control group）, total gastrectomy combined sptenectomy 16 cases（observation group）. Compare two groups the incidence of postoperative complications and 5-year survival rate and metastasis lymph node distribution. Results： The complication incidence of observation groupwas obviously higher than that of control group（31.3% vs 5.9%）, has statistically significant difference （P〈0.05）; 1 year survival rate of the observation group was significantly lower than the control group （37.5% vs 64.7%）, has statistically significant difference （P〈0.05）; Three and five years the survival rate of two groups had no statistical significance difference （P〉0.05）; No. 10 and 11 of metastasis lymph nodes of the observation group （6/23.1%） is significantly higher than control group （4/8.2%）, the difference has statistically significant （P〈0.05）. Conclusion： Splenectomy can not improve the survival rate of advanced gastric cancer;No spleen metastasis or 10, 11 groups of lymph node metas- tasis in patients with advanced gastric cancer should be careful to choose combined splenectomy.
出处
《中国现代普通外科进展》
CAS
2014年第9期697-699,703,共4页
Chinese Journal of Current Advances in General Surgery
关键词
进展期胃癌
全胃切除术
脾切除术
Advanced gastric canceroTotal gastrectomyoSplenectomy
