期刊文献+

驱动蛋白6基因多态性与心血管疾病相关性研究进展 被引量:2

下载PDF
导出
摘要 驱动蛋白6是驱动蛋白超家族中一类参与胞内转运的特殊蛋白质。近年来,研究发现驱动蛋白6基因 rs20455位点(Trp719Arg)单核苷酸多态性(single nucleotide polymor-phism ,SNP)可能与心血管疾病(cardiovascular diseases)易感性密切相关,且强化他汀类药物治疗可使驱动蛋白6基因变异者显著获益。本文就驱动蛋白6基因多态性与心血管疾病易感性关系的研究现状进行综述。
作者 陈娟 施建丰
出处 《国际检验医学杂志》 CAS 2014年第19期2663-2665,共3页 International Journal of Laboratory Medicine
  • 相关文献

参考文献27

  • 1Vale RT, Sheetz MR. Identification of a novel force-generating protein,kinesin,involved in microtubule-based motility[J]. Cell, 1985,42 (1) : :39-50. 被引量:1
  • 2Kaan HY, Hackney DD, Kozielski F. The structure o{ the kinesin 1 motor-tail complex reveals the mechanism of autoinhibition[J]. Sci- ence,2011,333 (644) : 883-885. 被引量:1
  • 3Vale RD, Milligan RA. The way things move: looking under the hood of molecular motor proteins[J]. Science, 2000,288 (5463) 88-95. 被引量:1
  • 4Asbury CL. Kinesin: world's tiniest biped[J]. Curr Opin Cell Biol, 2005,17(1) :89-97. 被引量:1
  • 5Miki H ,Okada Y, Hirokawa N. Analysis o{ t'he kinesin super{ami- ly :insights into structure and function[J]. Trends Cell Biol, 2005, 15(9) :467-476. 被引量:1
  • 6Mungall AS. The DNA sequence and analysis o{ human chromo- some 6[J]. Nature,2003,425(6960) :805-811. 被引量:1
  • 7Topoi EJ,Damani SB. The KIF6 eollapse[J]. J Am Coll Cardiol, 2010,56(19) :1564-1566. 被引量:1
  • 8Miki HOY, Hirokawa N. Analysis of the kinesin super{amily: in- sights into structure and function[J]. Trends Cell Biol, 2005,15 (9) :467-476. 被引量:1
  • 9Su AI,Cooke MP,Ching KA,et al. Large scale analysis of the hu man and mouse transcriptomes[J]. Proc Natl Acad Sci USA, 2002,99(7) : 4465-4470. 被引量:1
  • 10Bechtel S, Rosenfelder H, Duda A, et al. The full-ORF clone re- source of the German cDNA consortium[J]. BMC Genomics, 2007,8 : 399. 被引量:1

二级参考文献41

共引文献13

同被引文献17

  • 1许文燊,鄢盛恺,杨辉,夏良裕.KIF6基因rs20455多态性与中国北方汉族人冠心病及血脂水平的关联研究[J].中国分子心脏病学杂志,2011,11(6):350-354. 被引量:4
  • 2邱方,张葵,李雷,顾光煜,王丽,罗浔阳,夏永泉,顾平.人载脂蛋白基因A5 c.553 G>T多态性与冠心病及血脂水平的相关性研究[J].中华检验医学杂志,2007,30(7):753-756. 被引量:4
  • 3Davmli S, Gozalo C, Gand:ert S, et d. The polymorphism Trp719Arg in the kinesin-like protein 6 is associated with the presence of late out- growth endothelial progenitor ceils in acute myocm'dial infarction [ J ]. Atherosclerosis, 2010,210( 1 ) :48-50. 被引量:1
  • 4Piddini E, Sehmid JA, de Martin R, et al. The Ras-like CTPase Gem is involveed in cell shape lemode|ling and interacts with tile nowl ki- nesin-like protein KII9[J]. Emho J, 2001,20(15) :4076-40,87. 被引量:1
  • 5Bhanushali AA, Contractor A, Shah VT, et al. Investigation of KIF6 TrpT/9Arg in a case-control study of coronary artery disease in Western Indians[ J]. Molecules, 2011,15(12) :883-886. 被引量:1
  • 6Wu G, Li GB, Dai B. Association of KIF6 variant with lipid level and angiographie coronary artery disease events risk in the Han Chinese population[ J]. Molecules, 2012,17(9 ) :11:269-11280. 被引量:1
  • 7Shiffman D, Chasman DI, Zee RY, et al. A kinesin family memler 6 variant is associated with coronary heart disease in the Women's Heahh Study[J]. J Am Coll Cardiol, 2008,51(4):444--448. 被引量:1
  • 8Iakoubova OA, Tong CH, Rowland CM, et al. Association of the Tq3719Arg polymorphism in kinesin-like protein 6 with myocardial infarction and coronary heart disease in 2 prospective trials: the CARE and WOSCOPS trials [ J ]. J Am Coil Cardiol, 2008,51 (4) :435-443. 被引量:1
  • 9Iakoubova OA, Robertson M, Tong CH, ct al. KIF6 Trp719Arg polymorphism and the effect of statin therapy in elderly patients: resaltsfrom the PROSPER study[ J]. Eur J Cardiovasc Prey Reha- bil, 2010,17(4) :455-461. 被引量:1
  • 10Shiffman D, Sabatine MS, Louie JZ, et al. Effect of pravastatin therapy on coronary events in carriers of the KIF6 719Ag allele from the cholesterol and reeuren! everts trial[ J ]. Am J Cardio[, 2010,105 (9) :1300-1305. 被引量:1

引证文献2

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部