摘要
目的探讨双源CT（DSCT）对二尖瓣脱垂（MVP）诊断的可行性与临床应用价值。方法筛选20例3个月内同时行经胸超声心动图（TTE）及心脏DSCT检查的受检者,其中9例为MVP患者,11例为正常。由2名有心血管诊断经验的影像医师分别对20例受检者图像进行分析,测量脱垂幅度及二尖瓣厚度,并与TTE进行对比。结果 9例MVP患者,共10个脱垂瓣膜,DSCT诊断的敏感性80%～90%,特异性100%。且重复性好（同一观察者不同时间,不同观察者间一致性较好,k=0.925）。DSCT测量MVP幅度（3.95±1.43）mm）与超声测量值（4.22±1.41）mm差异无统计学意义（P=0.677）。MVP组中平均瓣膜厚度为（2.23±1.04）mm。结论与TTE相比,DSCT对MVP的诊断具有较好的敏感性及特异性,可作为MVP的检查方法之一。
Objective To investigate the feasibility of dual source CT （DSCT） angiography in diagnosing mitral valve prolapse （ MVP）, and to discuss its clinical apphcation. Methods The study cohort consisted of 20 patients who had undergone both transthoracic echocardiography （TTE） and DSCT angiography within 3 months. Among the 20 patients, MVP was confirmed in 9 and normal findings were seen in 11. The DSCT angiograms were analyzed by two experienced ra- diologists. The prolapse extent and the mitral valve thickness were determined, the results were compared with the data ob- tained by TTE. Results A total of 10 prolapsed leaflets were found in the 9 patients, and the diagnostic sensitivity and specificity by DSCT were 80% -90% and 100% respectively. The intra-observer agreement and inter-observer agreement were very high （K = 0. 925 ）. The excursion of billowing distance determined by DSCT and TTE were （3.95 ± 1.43 ） mm and （4.22± 1.41 ） mm respectively, and the difference was not statistically significant （P=0.677）. The leaflet thickness in patients with MVP was （2.23 ± 1.04） mm. Conclusion Compared with TTE, cardiac DSCT angiography has higher sensitivity and specificity in diagnosing mitral valve prolapse. Therefore, DSCT angiography can be used in clinical practice for the examination of mitral valve prolapse.
出处
《临床放射学杂志》
CSCD
北大核心
2014年第9期1335-1338,共4页
Journal of Clinical Radiology
