摘要
数字减影血管造影术（DSA）作为颅内动脉瘤（IAN）诊断金标准，其有创、检查费用昂贵以及对比剂肾毒性而应用受限。近30年来磁共振血管成像（MRA）技术快速发展，其无创性、高分辨力等特点使该技术可替代DSA应用于大部分动脉瘤患者的临床诊断和随访中，其中时间飞越MRA（time of flight magnetic resonance angiography，TOF-MRA）对直径小于5 mm的小动脉瘤诊断灵敏度达98.2%-98.7%；对比增强MRA （contrast enhanced MRA，CE-MRA）对颅内动脉瘤的灵敏度和特异度分别高达95%-100%和73%-100%；相位对比血管成像（phase contrast MRA，PC-MRA）对直径大于5 mm的颅内动脉瘤诊断特异度高达100%。上述血管成像技术均可清晰显示颅内动脉瘤，但其成像特点和临床应用范围各异。本文就不同MRA技术的方法、临床应用的选择、比较以及新进展做综述。
Although digital subtraction angiography （DSA） has been used as the gold standard for the diagnosis of intracranial aneurysms, its clinical use is somewhat limited by its invasiveness, high medical cost and potential risk of nephrotoxicity. For the past three decades, the magnetic resonance angiography （MRA） techniques have been developed rapidly. As a non-invasive technique with high resolution ability, MRA can replace DSA for the diagnosis of intracranial aneurysms in most clinical situations. The time-of-flight MRA （TOF-MRA） carries a diagnostic sensitivity of up to 98.2%-98.7%for tiny intracranial aneurysms （〈5 mm）, while the diagnostic sensitivity and specificity of contrast enhanced MRA （CE- MRA） for intracranial aneurysms are as high as 95% - 100% and 73% - 100% respectively. The diagnostic specificity of phase-contrast MRA （PC-MRA） for intracranial aneurysms （〉 5 mm） reaches as high as 100%. All the above mentioned MRA techniques can clearly display the intracranial aneurysms although their imaging characteristics and clinical applications are different from each other. This paper aims to make a brief review concerning the principles, clinical applications and recent progress of some MRA techniques.
出处
《介入放射学杂志》
CSCD
北大核心
2014年第9期826-830,共5页
Journal of Interventional Radiology
关键词
动脉瘤
磁共振血管成像
时间飞越法
相位对比法
对比增强
aneurysm
magnetic resonance angiography
time-of-flight technique
phase-contrast technique
contrast-enhancement
