摘要
[目的]了解本地区2型糖尿病（T2DM）患者合并泌尿系感染的病原菌分布以及耐药情况,为临床治疗提供可靠依据,指导临床合理用药.[方法]对2012年1月至2013年12月期间本院625例T2DM住院患者的尿细菌培养与药敏结果进行回顾性分析.[结果]在625例T2DM患者无菌中段尿中,捡出病原菌122株,革兰阴性杆菌占75.41％,其中无症状感染患者占43.58％.大肠埃希菌和肺炎克雷伯菌对氟喹诺酮类抗菌药物的耐药性大于60％.[结论]T2DM患者合并泌尿系感染,临床治疗应积极控制血糖,及早发现,根据药物敏感试验选用抗生素治疗.
[Objective]To understand the distribution and drug resistance of pathogenic bacteria of urinary tract infection in patients with type 2 diabetes mellitus in the area so as to provide reliable basis for clinical treatment and guide clinical rational drug use.[Methods] Urine bacteria culture and drug susceptibility results of 625 inpatients with type 2 diabetes mellitus in our hospital from Jan.2012 to Dec.2013 were analyzed retrospectively.[Results] The 122 strains pathogenic bacteria in midstream urine samples of 625 patients with type 2 diabetes mellitus were detected.Among these strains,gram-negative bacilli accounted for 75.41 ％.Patients with asymptomatic infection accounted for 43.58％.Drug resistance rate of Escherichia coli and Klebsiella pneumoniae to fluoroquinolone antibiotics were more than 60 ％.[Conclusion] For patients with type 2 diabetes mellitus merged by urinary tract infection,active glucose control,early detection and reasonable use of antibiotics according to antimicrobial susceptibility test should be taken in clinical treatment.
出处
《医学临床研究》
CAS
2014年第9期1761-1763,共3页
Journal of Clinical Research
